Detailed information of TA system TA056785

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 1269334..1270295
• Replicon: chromosome
• Accession: NZ_CP012621
• Organism: Zobellella denitrificans strain F13-1

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: AN401_RS06075
• Protein ID: WP_096778811.1
• Coordinates: 1269789..1270295 (+)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: AN401_RS06070
• Protein ID: WP_096778810.1
• Coordinates: 1269334..1269792 (+)
• Length: 153 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AN401_RS06060	1265628..1268540	-	2913	WP_096778809.1	DEAD/DEAH box helicase family protein	-
AN401_RS06065	1268537..1269058	-	522	WP_096780310.1	class I SAM-dependent methyltransferase	-
AN401_RS06070	1269334..1269792	+	459	WP_096778810.1	helix-turn-helix domain-containing protein	Antitoxin
AN401_RS06075	1269789..1270295	+	507	WP_096778811.1	PIN domain-containing protein	Toxin
AN401_RS06080	1270219..1271253	-	1035	WP_094039961.1	IS630 family transposase	-
AN401_RS19690	1271303..1271461	+	159	WP_157772161.1	hypothetical protein	-
AN401_RS06085	1271538..1272344	-	807	WP_096778812.1	tryptophan synthase subunit alpha	-
AN401_RS06090	1272341..1273534	-	1194	WP_094038994.1	tryptophan synthase subunit beta	-
AN401_RS06095	1273531..1274919	-	1389	WP_096778813.1	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (7-114)

Antitoxin

• SinI-like, DNA-binding domain (81-126)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18977.79 Da
• Isoelectric Point: 6.9585

>T56785 WP_096778811.1 NZ_CP012621:1269789-1270295 [Zobellella denitrificans]
MSSNYTVIYDACVMYPAPLRSLLMYLALSGQFRARWSNDIHREWMRNLLKNRPELDESKVERVRELMDSHVPGALVTGYE
RLIPGIVLPDPDDRHVVAAAIQTQAESIITFNLKDFPDDILAPFNIRAIHPDDFILTRRQNTSIMPHKRCAPIGSNFSPA
PTCAATSA

Nucleotide

• Length: 507 bp

>T56785 NZ_CP012621:1269789-1270295 [Zobellella denitrificans]
ATGAGCTCGAACTATACGGTCATCTACGATGCCTGTGTGATGTATCCGGCTCCCCTGAGGAGCTTGTTGATGTACCTGGC
GCTTTCCGGCCAGTTTCGGGCTCGCTGGTCGAATGATATCCACCGGGAATGGATGCGTAACCTGCTCAAAAATCGTCCTG
AACTCGATGAGTCAAAGGTCGAGAGAGTGCGTGAACTGATGGATAGTCATGTACCAGGTGCCTTGGTCACCGGCTATGAG
CGGCTTATTCCGGGCATTGTGCTGCCCGACCCGGATGATCGCCATGTGGTGGCCGCTGCGATTCAGACTCAGGCCGAGTC
GATTATCACCTTCAATTTGAAGGATTTTCCCGACGACATACTGGCTCCGTTTAATATAAGAGCGATCCACCCGGATGACT
TTATATTAACCCGGCGGCAAAATACATCGATTATGCCGCATAAGCGATGTGCTCCGATCGGAAGTAACTTTTCACCCGCT
CCGACCTGCGCTGCAACTTCCGCATAG

Antitoxin

Protein

• Length: 153 a.a.
• Molecular weight: 16859.25 Da
• Isoelectric Point: 5.2903

>AT56785 WP_096778810.1 NZ_CP012621:1269334-1269792 [Zobellella denitrificans]
MSRLQDTLPTQEEASLAKLCSQELSAILETRADTQTLAVTDQKGEVHRVKIPVSALRLLVDVLTELGEGNSVKLVPIHAE
LTSQEAADLLNVSRPTLIRLLDEGAIPFHRTGNRRKVKFADLRAYQQQLEQKRLASLSELSELDQALGMGYE

Nucleotide

• Length: 459 bp

>AT56785 NZ_CP012621:1269334-1269792 [Zobellella denitrificans]
ATGAGCCGTTTACAAGATACCTTGCCGACCCAGGAAGAAGCCAGTCTGGCCAAGCTCTGTAGCCAGGAGCTATCCGCGAT
TCTGGAAACCAGGGCGGATACCCAGACCCTGGCGGTTACCGATCAGAAGGGAGAAGTACACAGGGTCAAGATCCCGGTCA
GCGCCCTGCGCCTGCTGGTCGATGTACTGACCGAATTGGGAGAAGGGAATAGTGTCAAATTAGTCCCTATTCATGCCGAA
TTGACCAGCCAGGAAGCGGCGGATCTGCTGAATGTGTCGCGGCCAACTCTTATTCGCTTGCTCGACGAGGGCGCCATTCC
CTTCCATCGCACGGGAAATCGCCGCAAGGTGAAGTTTGCCGATCTGCGTGCCTATCAGCAGCAGCTTGAGCAGAAGCGAT
TGGCGAGCCTGTCCGAGCTGTCCGAGCTGGATCAGGCATTGGGGATGGGATACGAATGA