Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 856512..857106 Replicon chromosome
Accession NZ_CP012621
Organism Zobellella denitrificans strain F13-1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag AN401_RS04075 Protein ID WP_096778608.1
Coordinates 856512..856817 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag AN401_RS04080 Protein ID WP_096778609.1
Coordinates 856810..857106 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AN401_RS04050 851513..852736 + 1224 WP_096778603.1 site-specific integrase -
AN401_RS04055 852756..853691 + 936 WP_096778604.1 hypothetical protein -
AN401_RS04060 853780..853968 + 189 WP_096778605.1 AlpA family phage regulatory protein -
AN401_RS04065 853981..854460 + 480 WP_096778606.1 hypothetical protein -
AN401_RS04070 854724..856127 + 1404 WP_096778607.1 helix-turn-helix domain-containing protein -
AN401_RS04075 856512..856817 + 306 WP_096778608.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AN401_RS04080 856810..857106 + 297 WP_096778609.1 putative addiction module antidote protein Antitoxin
AN401_RS19665 857395..857559 + 165 WP_157772153.1 hypothetical protein -
AN401_RS19930 857544..857690 + 147 WP_198401876.1 hypothetical protein -
AN401_RS19670 858012..858155 - 144 WP_157772155.1 hypothetical protein -
AN401_RS04090 858223..858408 - 186 WP_096778611.1 hypothetical protein -
AN401_RS04095 859058..859357 - 300 WP_094038614.1 DNA-binding transcriptional regulator Fis -
AN401_RS04100 859384..860349 - 966 WP_094038613.1 tRNA dihydrouridine synthase DusB -
AN401_RS04105 860539..861414 - 876 WP_096778612.1 50S ribosomal protein L11 methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-95)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11503.18 Da        Isoelectric Point: 10.1603

>T56784 WP_096778608.1 NZ_CP012621:856512-856817 [Zobellella denitrificans]
MKVIESTKFRQWLKKLKDDTGRARVVSRINRLAAGLAGDVAPVGQGVSELRIHYGPGYRVYYYQQGEVLVLLLCGGDKGS
QRRDIETAHQLLKEWREQHHG

Download         Length: 306 bp

>T56784 NZ_CP012621:856512-856817 [Zobellella denitrificans]
ATGAAGGTGATCGAATCAACCAAGTTCCGGCAGTGGCTGAAGAAGCTGAAGGACGATACCGGTAGGGCCCGGGTAGTGTC
CCGGATCAACCGGCTGGCTGCCGGCCTGGCCGGCGACGTGGCCCCGGTGGGGCAGGGCGTTAGCGAACTGCGTATTCACT
ACGGGCCGGGCTACCGGGTTTACTACTACCAGCAGGGTGAGGTGCTGGTGTTGCTGCTATGCGGCGGCGACAAGGGAAGT
CAGCGCCGGGATATTGAGACCGCTCACCAGTTGTTGAAGGAATGGAGGGAACAGCACCATGGCTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10551.88 Da        Isoelectric Point: 4.6631

>AT56784 WP_096778609.1 NZ_CP012621:856810-857106 [Zobellella denitrificans]
MAEAFTEFDPAEYLSSPEAIAEFIADAMETGDAAYISKAIGIAARARGMSELARETGLSREQLYRSFSERGNPTLKTIMA
VTKALGVDITARAHVEHG

Download         Length: 297 bp

>AT56784 NZ_CP012621:856810-857106 [Zobellella denitrificans]
ATGGCTGAAGCATTCACCGAGTTCGACCCCGCCGAGTACCTGAGCAGCCCGGAGGCCATCGCCGAGTTTATCGCCGATGC
AATGGAGACCGGGGACGCCGCCTATATCTCCAAGGCGATCGGCATTGCCGCCCGCGCCAGGGGCATGAGCGAGCTGGCCA
GGGAAACCGGCCTGTCCCGCGAGCAGCTTTACCGGAGCTTCAGCGAACGGGGCAACCCGACCCTGAAGACCATCATGGCC
GTGACCAAGGCGCTGGGCGTGGACATTACCGCCCGTGCCCATGTTGAACATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References