Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2205838..2205983 Replicon chromosome
Accession NZ_CP012568
Organism Klebsiella pneumoniae strain UCLAOXA232KP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2205845..2205947 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2205838..2205983 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM278_RS11755 2201369..2202802 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM278_RS11760 2202918..2203157 + 240 WP_002911393.1 YebV family protein -
AM278_RS11765 2203255..2203446 + 192 WP_002911395.1 YebW family protein -
AM278_RS11770 2203443..2204096 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
AM278_RS11775 2204253..2205221 + 969 WP_004151446.1 VirK/YbjX family protein -
AM278_RS31035 2205326..2205469 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2205838..2205983 + 146 - - Antitoxin
- 2205845..2205947 - 103 - - Toxin
AM278_RS11790 2206106..2206444 - 339 WP_009307539.1 YebY family protein -
AM278_RS11795 2206461..2207330 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
AM278_RS11800 2207334..2207708 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM278_RS11805 2207821..2208051 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM278_RS11810 2208130..2208789 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM278_RS11815 2208793..2210853 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T56683 NZ_CP012568:c2205947-2205845 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT56683 NZ_CP012568:2205838-2205983 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References