Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2824700..2824845 Replicon chromosome
Accession NZ_CP012561
Organism Klebsiella pneumoniae strain UCLAOXA232KP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2824736..2824838 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2824700..2824845 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM277_RS14305 2819830..2821890 + 2061 WP_004151449.1 oligopeptidase B -
AM277_RS14310 2821894..2822553 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM277_RS14315 2822632..2822862 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM277_RS14320 2822975..2823349 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM277_RS14325 2823353..2824222 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
AM277_RS14330 2824239..2824577 + 339 WP_009307539.1 YebY family protein -
- 2824700..2824845 - 146 - - Antitoxin
- 2824736..2824838 + 103 - - Toxin
AM277_RS31720 2825214..2825357 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM277_RS14345 2825462..2826430 - 969 WP_004151446.1 VirK/YbjX family protein -
AM277_RS14350 2826587..2827240 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
AM277_RS14355 2827237..2827428 - 192 WP_002911395.1 YebW family protein -
AM277_RS14360 2827526..2827765 - 240 WP_002911393.1 YebV family protein -
AM277_RS14365 2827881..2829314 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T56666 NZ_CP012561:2824736-2824838 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT56666 NZ_CP012561:c2824845-2824700 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References