Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4221052..4221197 Replicon chromosome
Accession NZ_CP012560
Organism Klebsiella pneumoniae strain UCLAOXA232KP_Pt0

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4221088..4221190 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4221052..4221197 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM275_RS20755 4216182..4218242 + 2061 WP_004151449.1 oligopeptidase B -
AM275_RS20760 4218246..4218905 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM275_RS20765 4218984..4219214 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM275_RS20770 4219327..4219701 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM275_RS20775 4219705..4220574 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
AM275_RS20780 4220591..4220929 + 339 WP_009307539.1 YebY family protein -
- 4221052..4221197 - 146 - - Antitoxin
- 4221088..4221190 + 103 - - Toxin
AM275_RS28325 4221566..4221709 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AM275_RS20790 4221814..4222782 - 969 WP_004151446.1 VirK/YbjX family protein -
AM275_RS20795 4222939..4223592 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
AM275_RS20800 4223589..4223780 - 192 WP_002911395.1 YebW family protein -
AM275_RS20805 4223878..4224117 - 240 WP_002911393.1 YebV family protein -
AM275_RS20810 4224233..4225666 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T56650 NZ_CP012560:4221088-4221190 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT56650 NZ_CP012560:c4221197-4221052 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References