Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3765277..3765931 Replicon chromosome
Accession NZ_CP012554
Organism Citrobacter portucalensis strain P10159

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P10159_RS17885 Protein ID WP_060683279.1
Coordinates 3765524..3765931 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P10159_RS17880 Protein ID WP_003825514.1
Coordinates 3765277..3765543 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P10159_RS17855 3760432..3761865 - 1434 WP_060683276.1 6-phospho-beta-glucosidase BglA -
P10159_RS17860 3761986..3762714 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
P10159_RS17865 3762767..3763078 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
P10159_RS17870 3763242..3763904 + 663 WP_060683277.1 hemolysin III family protein -
P10159_RS17875 3764036..3765019 - 984 WP_060683278.1 tRNA-modifying protein YgfZ -
P10159_RS17880 3765277..3765543 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
P10159_RS17885 3765524..3765931 + 408 WP_060683279.1 protein YgfX Toxin
P10159_RS17890 3766033..3766554 - 522 WP_003026933.1 flavodoxin FldB -
P10159_RS17895 3766668..3767564 + 897 WP_003825519.1 site-specific tyrosine recombinase XerD -
P10159_RS17900 3767588..3768298 + 711 WP_060683280.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P10159_RS17905 3768304..3770037 + 1734 WP_048215591.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15898.76 Da        Isoelectric Point: 11.3523

>T56633 WP_060683279.1 NZ_CP012554:3765524-3765931 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINSCQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T56633 NZ_CP012554:3765524-3765931 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
GTTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACTCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCTGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGTATGATGCTACGCTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT56633 WP_003825514.1 NZ_CP012554:3765277-3765543 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT56633 NZ_CP012554:3765277-3765543 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References