Detailed information of TA system TA056625

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 1491839..1492341
• Replicon: chromosome
• Accession: NZ_CP012552
• Organism: Campylobacter sp. RM16192

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CDOMC_RS07905
• Protein ID: WP_172129169.1
• Coordinates: 1491839..1492114 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: CDOMC_RS07910
• Protein ID: WP_169943208.1
• Coordinates: 1492111..1492341 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDOMC_RS07885	1487540..1488430	+	891	WP_172129161.1	calcineurin phosphoesterase	-
CDOMC_RS07890	1489015..1489209	-	195	WP_172129163.1	hypothetical protein	-
CDOMC_RS07895	1489290..1490651	-	1362	WP_172129165.1	hypothetical protein	-
CDOMC_RS07900	1490658..1490927	-	270	WP_172129167.1	hypothetical protein	-
CDOMC_RS07905	1491839..1492114	-	276	WP_172129169.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CDOMC_RS07910	1492111..1492341	-	231	WP_169943208.1	ribbon-helix-helix domain-containing protein	Antitoxin
CDOMC_RS07915	1492498..1493997	-	1500	WP_172129682.1	response regulator	-
CDOMC_RS07920	1494525..1495367	+	843	WP_172129171.1	hypothetical protein	-
CDOMC_RS07925	1495448..1495753	-	306	WP_172129172.1	hypothetical protein	-
CDOMC_RS07930	1496072..1496434	-	363	WP_172129174.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-84)

Antitoxin

• Protein of unknown function DUF6290 (2-72)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10371.20 Da
• Isoelectric Point: 10.0794

>T56625 WP_172129169.1 NZ_CP012552:c1492114-1491839 [Campylobacter sp. RM16192]
MKVNFSKNALKELKKLDNSVGIKILKKLKEIEGLDNPRDEGKPLIGNLSGLWRYRVGGYRIICKIKDYKLIVLVLGVRNR
SDAYDGEFDSC

Nucleotide

• Length: 276 bp

>T56625 NZ_CP012552:c1492114-1491839 [Campylobacter sp. RM16192]
ATGAAAGTAAATTTCAGTAAAAATGCGTTAAAAGAGCTTAAGAAGTTAGATAATAGTGTTGGCATTAAAATACTTAAAAA
ACTAAAAGAGATAGAAGGCTTAGATAATCCTCGTGATGAAGGTAAACCACTTATAGGAAATCTATCCGGTCTTTGGAGAT
ATAGAGTCGGAGGATACAGAATAATATGCAAGATAAAAGATTATAAGCTTATAGTACTTGTACTTGGTGTTAGAAATAGA
AGCGATGCTTATGATGGTGAGTTTGATAGTTGTTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8941.28 Da
• Isoelectric Point: 4.8660

>AT56625 WP_169943208.1 NZ_CP012552:c1492341-1492111 [Campylobacter sp. RM16192]
MQISVRLDKDIGTKLERLAKDTKRTKSFYVQEAIKRFLEDMNDYIDAMEELKKIESDPNPQFYTLDEVAKELGVKI

Nucleotide

• Length: 231 bp

>AT56625 NZ_CP012552:c1492341-1492111 [Campylobacter sp. RM16192]
ATGCAAATTTCAGTTAGACTAGATAAAGATATAGGAACTAAGCTTGAGAGATTAGCAAAAGATACCAAACGAACAAAAAG
CTTTTACGTTCAAGAAGCTATAAAAAGATTCTTAGAAGATATGAATGATTATATAGATGCCATGGAAGAGTTAAAAAAGA
TAGAGAGTGATCCTAATCCTCAGTTTTATACTCTTGATGAAGTAGCTAAAGAGCTTGGCGTAAAAATATGA