Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1698106..1698637 | Replicon | chromosome |
| Accession | NZ_CP012549 | ||
| Organism | Campylobacter sp. RM16187 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | CDOMF_RS09045 | Protein ID | WP_260951655.1 |
| Coordinates | 1698347..1698637 (+) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | CDOMF_RS09040 | Protein ID | WP_260951653.1 |
| Coordinates | 1698106..1698357 (+) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CDOMF_RS09000 (CDOMF_1769) | 1693115..1693903 | + | 789 | WP_260951645.1 | hypothetical protein | - |
| CDOMF_RS09005 (CDOMF_1770) | 1694045..1694233 | + | 189 | WP_170020669.1 | helix-turn-helix domain-containing protein | - |
| CDOMF_RS09010 (CDOMF_1771) | 1694343..1694684 | + | 342 | WP_260951646.1 | hypothetical protein | - |
| CDOMF_RS09015 (CDOMF_1772) | 1694732..1694917 | + | 186 | WP_260951647.1 | hypothetical protein | - |
| CDOMF_RS09020 | 1694907..1695035 | + | 129 | WP_260951648.1 | hypothetical protein | - |
| CDOMF_RS09025 (CDOMF_1773) | 1695129..1695962 | + | 834 | WP_260951649.1 | phage antirepressor KilAC domain-containing protein | - |
| CDOMF_RS09030 (CDOMF_1774) | 1696021..1696767 | + | 747 | WP_260951650.1 | aspartate carbamoyltransferase | - |
| CDOMF_RS09035 (CDOMF_1776) | 1697470..1697658 | - | 189 | WP_260951651.1 | hypothetical protein | - |
| CDOMF_RS09040 (CDOMF_1777) | 1698106..1698357 | + | 252 | WP_260951653.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| CDOMF_RS09045 (CDOMF_1778) | 1698347..1698637 | + | 291 | WP_260951655.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| CDOMF_RS09050 (CDOMF_1779) | 1698658..1698873 | - | 216 | WP_260951656.1 | helix-turn-helix transcriptional regulator | - |
| CDOMF_RS09055 (CDOMF_1780) | 1699032..1699427 | + | 396 | WP_260951657.1 | hypothetical protein | - |
| CDOMF_RS09060 (CDOMF_1781) | 1699431..1699718 | + | 288 | WP_170020688.1 | hypothetical protein | - |
| CDOMF_RS09065 (CDOMF_1782) | 1699825..1700196 | + | 372 | WP_260951658.1 | hypothetical protein | - |
| CDOMF_RS09070 (CDOMF_1783) | 1700657..1700860 | + | 204 | WP_260951659.1 | hypothetical protein | - |
| CDOMF_RS09075 (CDOMF_1784) | 1700939..1701175 | + | 237 | WP_170020696.1 | hypothetical protein | - |
| CDOMF_RS09080 (CDOMF_1785) | 1701159..1701437 | + | 279 | WP_260951660.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CDOMF_RS09085 | 1702392..1702523 | + | 132 | WP_260951661.1 | hypothetical protein | - |
| CDOMF_RS09090 (CDOMF_1786) | 1702513..1703154 | + | 642 | WP_260951662.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11308.32 Da Isoelectric Point: 10.4729
>T56624 WP_260951655.1 NZ_CP012549:1698347-1698637 [Campylobacter sp. RM16187]
MSYELEFLPSALKEWQKLDNNIKAQFKKKLSARLANPRVAKDKLHGFDDIYKIKLKDAGYRLAYQVKDKEIIILVLVVGK
RENNQVYNTLKERVKK
MSYELEFLPSALKEWQKLDNNIKAQFKKKLSARLANPRVAKDKLHGFDDIYKIKLKDAGYRLAYQVKDKEIIILVLVVGK
RENNQVYNTLKERVKK
Download Length: 291 bp
>T56624 NZ_CP012549:1698347-1698637 [Campylobacter sp. RM16187]
ATGAGCTATGAATTGGAGTTTTTGCCAAGTGCCTTAAAAGAGTGGCAAAAGCTAGATAACAACATAAAGGCACAATTTAA
AAAGAAATTATCCGCTAGACTTGCAAACCCAAGAGTAGCAAAAGACAAACTACACGGATTTGACGACATCTACAAAATAA
AACTCAAAGACGCAGGCTATCGCCTAGCCTATCAAGTAAAAGACAAAGAAATAATAATTCTTGTCTTAGTGGTAGGCAAA
AGAGAAAATAACCAAGTATATAACACGCTAAAAGAGAGAGTTAAAAAGTGA
ATGAGCTATGAATTGGAGTTTTTGCCAAGTGCCTTAAAAGAGTGGCAAAAGCTAGATAACAACATAAAGGCACAATTTAA
AAAGAAATTATCCGCTAGACTTGCAAACCCAAGAGTAGCAAAAGACAAACTACACGGATTTGACGACATCTACAAAATAA
AACTCAAAGACGCAGGCTATCGCCTAGCCTATCAAGTAAAAGACAAAGAAATAATAATTCTTGTCTTAGTGGTAGGCAAA
AGAGAAAATAACCAAGTATATAACACGCTAAAAGAGAGAGTTAAAAAGTGA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9164.70 Da Isoelectric Point: 5.8171
>AT56624 WP_260951653.1 NZ_CP012549:1698106-1698357 [Campylobacter sp. RM16187]
MQTIQANVTASISELKKSPAQVIKQAGDEVVAILSHNVPSAYLVPSAVYEGMVEMMEDYKLIKEVKTALNSKEKPIKVKF
DEL
MQTIQANVTASISELKKSPAQVIKQAGDEVVAILSHNVPSAYLVPSAVYEGMVEMMEDYKLIKEVKTALNSKEKPIKVKF
DEL
Download Length: 252 bp
>AT56624 NZ_CP012549:1698106-1698357 [Campylobacter sp. RM16187]
ATGCAAACAATTCAAGCAAATGTTACAGCTAGCATTAGCGAGTTAAAGAAATCGCCTGCACAAGTTATTAAGCAAGCGGG
CGACGAAGTAGTAGCCATATTAAGCCATAATGTGCCGAGTGCTTATTTAGTGCCGAGTGCAGTATATGAGGGTATGGTTG
AGATGATGGAGGATTATAAACTTATCAAAGAGGTAAAAACAGCATTAAACAGCAAAGAAAAGCCGATAAAAGTAAAATTT
GATGAGCTATGA
ATGCAAACAATTCAAGCAAATGTTACAGCTAGCATTAGCGAGTTAAAGAAATCGCCTGCACAAGTTATTAAGCAAGCGGG
CGACGAAGTAGTAGCCATATTAAGCCATAATGTGCCGAGTGCTTATTTAGTGCCGAGTGCAGTATATGAGGGTATGGTTG
AGATGATGGAGGATTATAAACTTATCAAAGAGGTAAAAACAGCATTAAACAGCAAAGAAAAGCCGATAAAAGTAAAATTT
GATGAGCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|