Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1698106..1698637 Replicon chromosome
Accession NZ_CP012549
Organism Campylobacter sp. RM16187

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CDOMF_RS09045 Protein ID WP_260951655.1
Coordinates 1698347..1698637 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CDOMF_RS09040 Protein ID WP_260951653.1
Coordinates 1698106..1698357 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDOMF_RS09000 (CDOMF_1769) 1693115..1693903 + 789 WP_260951645.1 hypothetical protein -
CDOMF_RS09005 (CDOMF_1770) 1694045..1694233 + 189 WP_170020669.1 helix-turn-helix domain-containing protein -
CDOMF_RS09010 (CDOMF_1771) 1694343..1694684 + 342 WP_260951646.1 hypothetical protein -
CDOMF_RS09015 (CDOMF_1772) 1694732..1694917 + 186 WP_260951647.1 hypothetical protein -
CDOMF_RS09020 1694907..1695035 + 129 WP_260951648.1 hypothetical protein -
CDOMF_RS09025 (CDOMF_1773) 1695129..1695962 + 834 WP_260951649.1 phage antirepressor KilAC domain-containing protein -
CDOMF_RS09030 (CDOMF_1774) 1696021..1696767 + 747 WP_260951650.1 aspartate carbamoyltransferase -
CDOMF_RS09035 (CDOMF_1776) 1697470..1697658 - 189 WP_260951651.1 hypothetical protein -
CDOMF_RS09040 (CDOMF_1777) 1698106..1698357 + 252 WP_260951653.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CDOMF_RS09045 (CDOMF_1778) 1698347..1698637 + 291 WP_260951655.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CDOMF_RS09050 (CDOMF_1779) 1698658..1698873 - 216 WP_260951656.1 helix-turn-helix transcriptional regulator -
CDOMF_RS09055 (CDOMF_1780) 1699032..1699427 + 396 WP_260951657.1 hypothetical protein -
CDOMF_RS09060 (CDOMF_1781) 1699431..1699718 + 288 WP_170020688.1 hypothetical protein -
CDOMF_RS09065 (CDOMF_1782) 1699825..1700196 + 372 WP_260951658.1 hypothetical protein -
CDOMF_RS09070 (CDOMF_1783) 1700657..1700860 + 204 WP_260951659.1 hypothetical protein -
CDOMF_RS09075 (CDOMF_1784) 1700939..1701175 + 237 WP_170020696.1 hypothetical protein -
CDOMF_RS09080 (CDOMF_1785) 1701159..1701437 + 279 WP_260951660.1 type II toxin-antitoxin system RelE/ParE family toxin -
CDOMF_RS09085 1702392..1702523 + 132 WP_260951661.1 hypothetical protein -
CDOMF_RS09090 (CDOMF_1786) 1702513..1703154 + 642 WP_260951662.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11308.32 Da        Isoelectric Point: 10.4729

>T56624 WP_260951655.1 NZ_CP012549:1698347-1698637 [Campylobacter sp. RM16187]
MSYELEFLPSALKEWQKLDNNIKAQFKKKLSARLANPRVAKDKLHGFDDIYKIKLKDAGYRLAYQVKDKEIIILVLVVGK
RENNQVYNTLKERVKK

Download         Length: 291 bp

>T56624 NZ_CP012549:1698347-1698637 [Campylobacter sp. RM16187]
ATGAGCTATGAATTGGAGTTTTTGCCAAGTGCCTTAAAAGAGTGGCAAAAGCTAGATAACAACATAAAGGCACAATTTAA
AAAGAAATTATCCGCTAGACTTGCAAACCCAAGAGTAGCAAAAGACAAACTACACGGATTTGACGACATCTACAAAATAA
AACTCAAAGACGCAGGCTATCGCCTAGCCTATCAAGTAAAAGACAAAGAAATAATAATTCTTGTCTTAGTGGTAGGCAAA
AGAGAAAATAACCAAGTATATAACACGCTAAAAGAGAGAGTTAAAAAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9164.70 Da        Isoelectric Point: 5.8171

>AT56624 WP_260951653.1 NZ_CP012549:1698106-1698357 [Campylobacter sp. RM16187]
MQTIQANVTASISELKKSPAQVIKQAGDEVVAILSHNVPSAYLVPSAVYEGMVEMMEDYKLIKEVKTALNSKEKPIKVKF
DEL

Download         Length: 252 bp

>AT56624 NZ_CP012549:1698106-1698357 [Campylobacter sp. RM16187]
ATGCAAACAATTCAAGCAAATGTTACAGCTAGCATTAGCGAGTTAAAGAAATCGCCTGCACAAGTTATTAAGCAAGCGGG
CGACGAAGTAGTAGCCATATTAAGCCATAATGTGCCGAGTGCTTATTTAGTGCCGAGTGCAGTATATGAGGGTATGGTTG
AGATGATGGAGGATTATAAACTTATCAAAGAGGTAAAAACAGCATTAAACAGCAAAGAAAAGCCGATAAAAGTAAAATTT
GATGAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References