Detailed information of TA system TA056620

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 1567700..1568202
• Replicon: chromosome
• Accession: NZ_CP012547
• Organism: Campylobacter pinnipediorum subsp. pinnipediorum strain RM17261

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CPIN17261_RS07985
• Protein ID: WP_078388067.1
• Coordinates: 1567927..1568202 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: CPIN17261_RS07980
• Protein ID: WP_078388066.1
• Coordinates: 1567700..1567930 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPIN17261_RS07965	1563904..1564119	-	216	WP_069633282.1	DUF4492 domain-containing protein	-
CPIN17261_RS07970	1564282..1565913	+	1632	WP_078388064.1	CTP synthase	-
CPIN17261_RS07975	1565903..1567474	+	1572	WP_078388065.1	single-stranded-DNA-specific exonuclease RecJ	-
CPIN17261_RS07980	1567700..1567930	+	231	WP_078388066.1	ribbon-helix-helix domain-containing protein	Antitoxin
CPIN17261_RS07985	1567927..1568202	+	276	WP_078388067.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CPIN17261_RS07990	1568559..1571822	-	3264	WP_078388068.1	carbamoyl-phosphate synthase large subunit	-
CPIN17261_RS07995	1571822..1572577	-	756	WP_069633277.1	rod shape-determining protein MreC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-83)

Antitoxin

• Relaxosome protein TraY (3-35)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10431.23 Da
• Isoelectric Point: 10.1278

>T56620 WP_078388067.1 NZ_CP012547:1567927-1568202 [Campylobacter pinnipediorum subsp. pinnipediorum]
MKISFSKNALKEVKKLDKSVGIKILKKLKEIESLDNPRDEGKPLVGNLSGLWRYRVGGYRIICKIKDHELIVLILGIKNR
NNAYDSEFDSE

Nucleotide

• Length: 276 bp

>T56620 NZ_CP012547:1567927-1568202 [Campylobacter pinnipediorum subsp. pinnipediorum]
ATGAAAATAAGTTTTAGTAAAAATGCATTAAAAGAGGTTAAAAAGCTAGATAAGAGTGTTGGTATTAAAATACTTAAAAA
GTTAAAAGAAATAGAAAGTTTAGACAATCCTCGCGATGAAGGTAAACCTCTTGTCGGAAATTTATCTGGTCTTTGGAGAT
ATAGAGTTGGGGGATATAGAATAATATGCAAGATAAAAGATCACGAACTTATAGTGCTTATACTAGGCATTAAAAACAGG
AATAATGCTTACGATAGTGAGTTTGATAGCGAATAG

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8972.26 Da
• Isoelectric Point: 4.6583

>AT56620 WP_078388066.1 NZ_CP012547:1567700-1567930 [Campylobacter pinnipediorum subsp. pinnipediorum]
MQISVRLDKDIGNKLERLAKDTKRTKSFYVQEAIKRFLEDMNDYMYAVEELKKIENDPNPEFYALDEVAKDLGINL

Nucleotide

• Length: 231 bp

>AT56620 NZ_CP012547:1567700-1567930 [Campylobacter pinnipediorum subsp. pinnipediorum]
ATGCAAATTTCAGTTAGATTAGATAAAGATATAGGAAACAAGCTTGAGAGATTAGCAAAAGATACAAAAAGAACAAAAAG
CTTTTATGTCCAAGAAGCTATAAAAAGATTCTTAGAAGATATGAATGACTATATGTATGCAGTAGAAGAGTTAAAAAAAA
TAGAAAATGATCCTAATCCAGAATTTTATGCCTTAGATGAAGTAGCCAAAGATCTTGGCATAAACCTATGA