Detailed information of TA system
Overview
TA module
Type | II | Classification (family/domain) | PumA-relB/upstrm_HI1419-dnstrm_HI1420 |
Location | 881777..882353 | Replicon | chromosome |
Accession | NZ_CP012547 | ||
Organism | Campylobacter pinnipediorum subsp. pinnipediorum strain RM17261 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | CPIN17261_RS04425 | Protein ID | WP_078387706.1 |
Coordinates | 881777..882076 (+) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | CPIN17261_RS04430 | Protein ID | WP_078387707.1 |
Coordinates | 882069..882353 (+) | Length | 95 a.a. |
Genomic Context
Location: 876860..877201 (342 bp)
Type: Others
Protein ID: WP_078387698.1
Type: Others
Protein ID: WP_078387698.1
Location: 877203..877508 (306 bp)
Type: Others
Protein ID: WP_194284709.1
Type: Others
Protein ID: WP_194284709.1
Location: 877546..878748 (1203 bp)
Type: Others
Protein ID: WP_078387700.1
Type: Others
Protein ID: WP_078387700.1
Location: 878738..878923 (186 bp)
Type: Others
Protein ID: WP_078387701.1
Type: Others
Protein ID: WP_078387701.1
Location: 878913..879443 (531 bp)
Type: Others
Protein ID: WP_078387702.1
Type: Others
Protein ID: WP_078387702.1
Location: 879454..879678 (225 bp)
Type: Others
Protein ID: WP_078387703.1
Type: Others
Protein ID: WP_078387703.1
Location: 879669..881372 (1704 bp)
Type: Others
Protein ID: WP_078387704.1
Type: Others
Protein ID: WP_078387704.1
Location: 881777..882076 (300 bp)
Type: Toxin
Protein ID: WP_078387706.1
Type: Toxin
Protein ID: WP_078387706.1
Location: 882069..882353 (285 bp)
Type: Antitoxin
Protein ID: WP_078387707.1
Type: Antitoxin
Protein ID: WP_078387707.1
Location: 884859..885041 (183 bp)
Type: Others
Protein ID: WP_078387711.1
Type: Others
Protein ID: WP_078387711.1
Location: 881460..881669 (210 bp)
Type: Others
Protein ID: WP_078387705.1
Type: Others
Protein ID: WP_078387705.1
Location: 882356..883357 (1002 bp)
Type: Others
Protein ID: WP_153300937.1
Type: Others
Protein ID: WP_153300937.1
Location: 883700..884782 (1083 bp)
Type: Others
Protein ID: WP_078387710.1
Type: Others
Protein ID: WP_078387710.1
Location: 885146..885409 (264 bp)
Type: Others
Protein ID: WP_078387712.1
Type: Others
Protein ID: WP_078387712.1
Location: 885480..885974 (495 bp)
Type: Others
Protein ID: WP_078387713.1
Type: Others
Protein ID: WP_078387713.1
Location: 885979..886227 (249 bp)
Type: Others
Protein ID: WP_078387714.1
Type: Others
Protein ID: WP_078387714.1
Location: 886230..886466 (237 bp)
Type: Others
Protein ID: WP_078387715.1
Type: Others
Protein ID: WP_078387715.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CPIN17261_RS04385 | 876860..877201 | + | 342 | WP_078387698.1 | hypothetical protein | - |
CPIN17261_RS04390 | 877203..877508 | + | 306 | WP_194284709.1 | hypothetical protein | - |
CPIN17261_RS04395 | 877546..878748 | + | 1203 | WP_078387700.1 | hypothetical protein | - |
CPIN17261_RS04400 | 878738..878923 | + | 186 | WP_078387701.1 | hypothetical protein | - |
CPIN17261_RS04405 | 878913..879443 | + | 531 | WP_078387702.1 | hypothetical protein | - |
CPIN17261_RS04410 | 879454..879678 | + | 225 | WP_078387703.1 | hypothetical protein | - |
CPIN17261_RS04415 | 879669..881372 | + | 1704 | WP_078387704.1 | AAA family ATPase | - |
CPIN17261_RS04420 | 881460..881669 | - | 210 | WP_078387705.1 | hypothetical protein | - |
CPIN17261_RS04425 | 881777..882076 | + | 300 | WP_078387706.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CPIN17261_RS04430 | 882069..882353 | + | 285 | WP_078387707.1 | putative addiction module antidote protein | Antitoxin |
CPIN17261_RS04435 | 882356..883357 | - | 1002 | WP_153300937.1 | hypothetical protein | - |
CPIN17261_RS04445 | 883700..884782 | - | 1083 | WP_078387710.1 | phage tail tape measure protein | - |
CPIN17261_RS04450 | 884859..885041 | + | 183 | WP_078387711.1 | hypothetical protein | - |
CPIN17261_RS04455 | 885146..885409 | - | 264 | WP_078387712.1 | hypothetical protein | - |
CPIN17261_RS04460 | 885480..885974 | - | 495 | WP_078387713.1 | phage major tail tube protein | - |
CPIN17261_RS04465 | 885979..886227 | - | 249 | WP_078387714.1 | hypothetical protein | - |
CPIN17261_RS04470 | 886230..886466 | - | 237 | WP_078387715.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 863364..913542 | 50178 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11373.05 Da Isoelectric Point: 9.6254
>T56619 WP_078387706.1 NZ_CP012547:881777-882076 [Campylobacter pinnipediorum subsp. pinnipediorum]
MYTIKQTDYFSKWIIKLKDIKGKVSILRRVERIKDGNFGDCKSVGNNISELRITTGPGYRVYYTNKNDEIIILLVGGDKS
TQSNDIKKANEILKDLENE
MYTIKQTDYFSKWIIKLKDIKGKVSILRRVERIKDGNFGDCKSVGNNISELRITTGPGYRVYYTNKNDEIIILLVGGDKS
TQSNDIKKANEILKDLENE
Download Length: 300 bp
>T56619 NZ_CP012547:881777-882076 [Campylobacter pinnipediorum subsp. pinnipediorum]
ATGTATACAATAAAACAAACTGATTACTTTTCAAAATGGATAATAAAGCTTAAAGACATAAAGGGTAAAGTTTCAATTTT
GCGAAGAGTTGAAAGAATAAAAGACGGCAATTTTGGAGATTGTAAATCAGTTGGTAACAATATAAGCGAACTAAGAATTA
CAACTGGTCCAGGATATAGAGTTTATTACACAAATAAAAACGATGAGATTATTATTTTATTAGTTGGCGGGGATAAATCA
ACTCAAAGTAATGATATTAAAAAAGCAAATGAAATTTTAAAGGATTTAGAAAATGAGTAA
ATGTATACAATAAAACAAACTGATTACTTTTCAAAATGGATAATAAAGCTTAAAGACATAAAGGGTAAAGTTTCAATTTT
GCGAAGAGTTGAAAGAATAAAAGACGGCAATTTTGGAGATTGTAAATCAGTTGGTAACAATATAAGCGAACTAAGAATTA
CAACTGGTCCAGGATATAGAGTTTATTACACAAATAAAAACGATGAGATTATTATTTTATTAGTTGGCGGGGATAAATCA
ACTCAAAGTAATGATATTAAAAAAGCAAATGAAATTTTAAAGGATTTAGAAAATGAGTAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10394.93 Da Isoelectric Point: 5.0477
>AT56619 WP_078387707.1 NZ_CP012547:882069-882353 [Campylobacter pinnipediorum subsp. pinnipediorum]
MSKTQITDFDISQYLDNQEVIAEYISQILADGDMDELLDALGNIAKAKGMSQIAKDTGLGRESLYKTFHKGSKPKFDTIM
KLISSFGLKMQVSA
MSKTQITDFDISQYLDNQEVIAEYISQILADGDMDELLDALGNIAKAKGMSQIAKDTGLGRESLYKTFHKGSKPKFDTIM
KLISSFGLKMQVSA
Download Length: 285 bp
>AT56619 NZ_CP012547:882069-882353 [Campylobacter pinnipediorum subsp. pinnipediorum]
ATGAGTAAAACACAAATAACGGATTTTGATATATCTCAGTATTTAGACAATCAAGAAGTCATAGCAGAATATATATCTCA
AATCTTAGCCGATGGTGATATGGATGAGCTACTAGATGCGCTTGGCAATATAGCAAAAGCCAAAGGCATGAGCCAAATAG
CAAAAGACACAGGGCTGGGCAGAGAAAGTTTATATAAAACCTTTCACAAAGGAAGTAAGCCAAAGTTTGATACTATAATG
AAACTTATATCTTCTTTTGGTTTAAAAATGCAAGTTAGCGCATAA
ATGAGTAAAACACAAATAACGGATTTTGATATATCTCAGTATTTAGACAATCAAGAAGTCATAGCAGAATATATATCTCA
AATCTTAGCCGATGGTGATATGGATGAGCTACTAGATGCGCTTGGCAATATAGCAAAAGCCAAAGGCATGAGCCAAATAG
CAAAAGACACAGGGCTGGGCAGAGAAAGTTTATATAAAACCTTTCACAAAGGAAGTAAGCCAAAGTTTGATACTATAATG
AAACTTATATCTTCTTTTGGTTTAAAAATGCAAGTTAGCGCATAA