Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 945850..946426 Replicon chromosome
Accession NZ_CP012546
Organism Campylobacter pinnipediorum subsp. pinnipediorum strain RM17260

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CPIN17260_RS04865 Protein ID WP_078440649.1
Coordinates 945850..946149 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CPIN17260_RS04870 Protein ID WP_078387707.1
Coordinates 946142..946426 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPIN17260_RS04825 940927..941268 + 342 WP_078387698.1 hypothetical protein -
CPIN17260_RS04830 941274..941576 + 303 WP_099046655.1 hypothetical protein -
CPIN17260_RS04835 941614..942816 + 1203 WP_078440645.1 hypothetical protein -
CPIN17260_RS04840 942806..942991 + 186 WP_078387701.1 hypothetical protein -
CPIN17260_RS04845 942981..943520 + 540 WP_078440646.1 hypothetical protein -
CPIN17260_RS04850 943527..943751 + 225 WP_078440647.1 hypothetical protein -
CPIN17260_RS04855 943742..945445 + 1704 WP_078440648.1 AAA family ATPase -
CPIN17260_RS04860 945533..945742 - 210 WP_078387705.1 hypothetical protein -
CPIN17260_RS04865 945850..946149 + 300 WP_078440649.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CPIN17260_RS04870 946142..946426 + 285 WP_078387707.1 putative addiction module antidote protein Antitoxin
CPIN17260_RS04875 946429..947355 - 927 WP_078440650.1 hypothetical protein -
CPIN17260_RS04880 947354..947620 + 267 WP_078387709.1 hypothetical protein -
CPIN17260_RS04885 947773..948855 - 1083 WP_078387710.1 phage tail tape measure protein -
CPIN17260_RS04890 948932..949114 + 183 WP_078387711.1 hypothetical protein -
CPIN17260_RS04895 949219..949482 - 264 WP_078415519.1 hypothetical protein -
CPIN17260_RS04900 949553..950047 - 495 WP_078440651.1 phage major tail tube protein -
CPIN17260_RS04905 950052..950300 - 249 WP_078440652.1 hypothetical protein -
CPIN17260_RS04910 950303..950539 - 237 WP_078440653.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 927458..975759 48301


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11415.09 Da        Isoelectric Point: 9.6406

>T56618 WP_078440649.1 NZ_CP012546:945850-946149 [Campylobacter pinnipediorum subsp. pinnipediorum]
MYTIKQTDYFSKWLIKLKDIRGKVSILRRIERIKDGNFGDCKSVGNNISELRITTGPGYRVYYTNKNDEIIILLVGGDKS
TQSNDIKKANEILKDLENE

Download         Length: 300 bp

>T56618 NZ_CP012546:945850-946149 [Campylobacter pinnipediorum subsp. pinnipediorum]
ATGTATACAATAAAACAAACTGATTACTTTTCAAAATGGCTAATAAAGCTTAAAGATATAAGGGGCAAAGTTTCAATTTT
GCGAAGAATTGAAAGAATAAAAGATGGTAACTTTGGAGATTGCAAATCAGTTGGTAACAATATAAGCGAACTAAGAATTA
CAACTGGTCCAGGATATAGAGTTTATTACACAAATAAAAACGATGAGATTATTATTTTATTAGTTGGCGGGGATAAATCA
ACTCAAAGTAATGATATTAAAAAAGCAAATGAAATTTTAAAGGATTTAGAAAATGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10394.93 Da        Isoelectric Point: 5.0477

>AT56618 WP_078387707.1 NZ_CP012546:946142-946426 [Campylobacter pinnipediorum subsp. pinnipediorum]
MSKTQITDFDISQYLDNQEVIAEYISQILADGDMDELLDALGNIAKAKGMSQIAKDTGLGRESLYKTFHKGSKPKFDTIM
KLISSFGLKMQVSA

Download         Length: 285 bp

>AT56618 NZ_CP012546:946142-946426 [Campylobacter pinnipediorum subsp. pinnipediorum]
ATGAGTAAAACACAAATAACGGATTTTGATATATCTCAGTATTTAGACAATCAAGAAGTCATAGCAGAATATATATCTCA
AATCTTAGCCGATGGTGATATGGATGAGTTACTAGACGCACTTGGCAATATAGCAAAAGCCAAAGGCATGAGCCAAATAG
CAAAAGACACAGGGCTGGGCAGAGAAAGTTTATATAAAACCTTTCACAAAGGAAGTAAACCAAAGTTTGATACTATAATG
AAACTTATATCTTCTTTTGGTTTAAAAATGCAAGTTAGCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References