Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 2383855..2384380 Replicon chromosome
Accession NZ_CP012543
Organism Campylobacter rectus strain ATCC 33238

Toxin (Protein)


Gene name relE Uniprot ID B9D2N3
Locus tag CRECT_RS11450 Protein ID WP_002944901.1
Coordinates 2383855..2384139 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B9D2N2
Locus tag CRECT_RS11455 Protein ID WP_002944882.1
Coordinates 2384129..2384380 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRECT_RS11430 2378995..2380539 + 1545 WP_002944912.1 fatty acid--CoA ligase -
CRECT_RS11435 2380539..2382260 + 1722 WP_002944916.1 ATP-binding protein -
CRECT_RS11440 2382285..2383445 + 1161 WP_002944903.1 hypothetical protein -
CRECT_RS11445 2383591..2383842 + 252 WP_100067273.1 hypothetical protein -
CRECT_RS11450 2383855..2384139 - 285 WP_002944901.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CRECT_RS11455 2384129..2384380 - 252 WP_002944882.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CRECT_RS11460 2384470..2386305 - 1836 WP_002944862.1 dynamin family protein -
CRECT_RS11465 2386298..2388865 - 2568 WP_002944909.1 dynamin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11089.93 Da        Isoelectric Point: 9.9155

>T56617 WP_002944901.1 NZ_CP012543:c2384139-2383855 [Campylobacter rectus]
MSYELEFLPSALKEWQKLDNSVKAQFKKKLAERLENPKVAKDKLRGYENIYKIKLKDAGYRLAYQVKDAQITIIVLVVGR
RENDEAYELLKDRI

Download         Length: 285 bp

>T56617 NZ_CP012543:c2384139-2383855 [Campylobacter rectus]
ATGAGCTATGAGTTAGAGTTTTTACCTAGCGCTTTAAAAGAGTGGCAAAAACTGGATAATAGCGTAAAGGCGCAGTTTAA
AAAGAAGCTCGCCGAGCGCCTAGAAAATCCCAAAGTAGCTAAGGATAAACTACGCGGCTATGAAAATATCTACAAAATCA
AGTTAAAGGATGCGGGCTACCGACTAGCCTATCAAGTAAAAGACGCCCAGATAACAATCATAGTTTTAGTCGTCGGCAGA
AGAGAAAACGATGAAGCGTATGAGTTGCTAAAAGATAGAATTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9022.43 Da        Isoelectric Point: 6.4567

>AT56617 WP_002944882.1 NZ_CP012543:c2384380-2384129 [Campylobacter rectus]
MQTIQANFTASISELKKSPAQILKQAKGNVVAILNHNVPSAYLVPSAVYEKMIEIIDDYHLNKAVDTALASGEKPVKVSL
DEL

Download         Length: 252 bp

>AT56617 NZ_CP012543:c2384380-2384129 [Campylobacter rectus]
ATGCAAACCATACAAGCAAATTTTACCGCTAGCATAAGCGAGCTAAAAAAATCTCCGGCTCAAATTTTAAAGCAAGCAAA
GGGCAATGTCGTAGCGATACTAAACCATAACGTGCCTAGCGCCTATCTGGTACCAAGCGCCGTGTATGAAAAGATGATCG
AAATAATAGACGACTATCATCTAAATAAAGCCGTAGATACTGCGCTGGCAAGTGGCGAAAAGCCCGTAAAAGTAAGCTTA
GATGAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G5QQD3

Antitoxin

Source ID Structure
AlphaFold DB A0A6G5QQA1

References