Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1895610..1896138 Replicon chromosome
Accession NZ_CP012529
Organism Psychrobacter sp. P2G3

Toxin (Protein)


Gene name relE Uniprot ID A0A7U4QQF5
Locus tag AK823_RS07735 Protein ID WP_068327992.1
Coordinates 1895851..1896138 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U4TJQ9
Locus tag AK823_RS07730 Protein ID WP_068327990.1
Coordinates 1895610..1895861 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AK823_RS07720 1891456..1893732 + 2277 WP_068327986.1 ribonucleoside-diphosphate reductase subunit alpha -
AK823_RS07725 1893836..1894789 + 954 WP_149031851.1 DUF2971 domain-containing protein -
AK823_RS07730 1895610..1895861 + 252 WP_068327990.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AK823_RS07735 1895851..1896138 + 288 WP_068327992.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
AK823_RS07740 1896162..1896533 + 372 WP_068327995.1 hypothetical protein -
AK823_RS07745 1896631..1897764 + 1134 WP_068327998.1 ribonucleotide-diphosphate reductase subunit beta -
AK823_RS07750 1898012..1898278 + 267 WP_068036052.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
AK823_RS07755 1898380..1899726 - 1347 WP_068328001.1 trypsin-like peptidase domain-containing protein -
AK823_RS07760 1900075..1900917 + 843 WP_068328003.1 Nif3-like dinuclear metal center hexameric protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-68)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11085.05 Da        Isoelectric Point: 10.6783

>T56613 WP_068327992.1 NZ_CP012529:1895851-1896138 [Psychrobacter sp. P2G3]
MTYNLEFHPLALKEWKKLAPSIQQQFKKKLQQRLLNPRVPASKLSGHTDAYKIKLRTIGYRLVYTVKDDVVVVYVLAVGK
RENNKVYESLVSRQP

Download         Length: 288 bp

>T56613 NZ_CP012529:1895851-1896138 [Psychrobacter sp. P2G3]
ATGACTTATAATCTTGAGTTTCATCCTTTAGCATTAAAAGAATGGAAAAAGTTAGCGCCCAGTATTCAGCAGCAGTTTAA
GAAAAAATTACAGCAGCGCTTATTAAACCCTCGTGTTCCTGCTTCAAAACTCTCGGGACATACAGACGCCTATAAAATCA
AACTACGCACCATAGGCTATCGTCTGGTTTATACCGTAAAAGATGATGTAGTGGTGGTTTATGTGCTAGCCGTAGGCAAA
AGAGAAAACAATAAGGTATATGAAAGCCTTGTGTCACGCCAACCATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9088.39 Da        Isoelectric Point: 4.2493

>AT56613 WP_068327990.1 NZ_CP012529:1895610-1895861 [Psychrobacter sp. P2G3]
MQPIFATQTASISELKANPSALIKQSDGESIAILNHNKPVAYLVSTDMYERMMEAMDDMALSQTVSARMNDGQVPVKVTL
DDL

Download         Length: 252 bp

>AT56613 NZ_CP012529:1895610-1895861 [Psychrobacter sp. P2G3]
ATGCAACCGATATTTGCGACACAGACAGCTAGCATCTCAGAACTAAAGGCCAACCCTTCGGCACTAATTAAACAGTCGGA
TGGTGAATCCATTGCTATTTTAAATCATAACAAACCTGTGGCTTATTTAGTTTCAACAGATATGTATGAGCGCATGATGG
AAGCGATGGACGATATGGCATTAAGCCAAACCGTTAGCGCACGAATGAATGACGGGCAAGTACCTGTAAAGGTAACGTTG
GATGACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U4QQF5

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4TJQ9

References