Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4877563..4877708 Replicon chromosome
Accession NZ_CP012426
Organism Klebsiella pneumoniae strain KP5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4877599..4877701 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4877563..4877708 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACG94_RS24440 4872693..4874753 + 2061 WP_004151449.1 oligopeptidase B -
ACG94_RS24445 4874757..4875416 - 660 WP_002911407.1 exodeoxyribonuclease X -
ACG94_RS24450 4875495..4875725 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ACG94_RS24455 4875838..4876212 + 375 WP_039819395.1 CopC domain-containing protein YobA -
ACG94_RS24460 4876216..4877085 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
ACG94_RS24465 4877102..4877440 + 339 WP_002911404.1 YebY family protein -
- 4877563..4877708 - 146 - - Antitoxin
- 4877599..4877701 + 103 - - Toxin
ACG94_RS30420 4878077..4878220 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
ACG94_RS24475 4878325..4879293 - 969 WP_014907334.1 VirK/YbjX family protein -
ACG94_RS24480 4879450..4880103 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
ACG94_RS24485 4880100..4880291 - 192 WP_002911395.1 YebW family protein -
ACG94_RS24490 4880389..4880628 - 240 WP_002911393.1 YebV family protein -
ACG94_RS24495 4880744..4882177 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T56467 NZ_CP012426:4877599-4877701 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT56467 NZ_CP012426:c4877708-4877563 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References