Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2292767..2294246 Replicon chromosome
Accession NZ_CP012398
Organism Chelatococcus sp. CO-6

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag AL346_RS10740 Protein ID WP_019400650.1
Coordinates 2293377..2294246 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag AL346_RS10735 Protein ID WP_026014859.1
Coordinates 2292767..2293384 (+) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL346_RS10715 2288202..2290310 - 2109 WP_019400655.1 ParB/RepB/Spo0J family partition protein -
AL346_RS10720 2290486..2290974 - 489 WP_050996451.1 DNA repair protein RadC -
AL346_RS10725 2291095..2291499 - 405 WP_019400653.1 DUF2958 domain-containing protein -
AL346_RS10730 2291496..2292455 - 960 WP_019400652.1 DUF1738 domain-containing protein -
AL346_RS10735 2292767..2293384 + 618 WP_026014859.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
AL346_RS10740 2293377..2294246 + 870 WP_019400650.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
AL346_RS10745 2294278..2294727 - 450 WP_019400649.1 DNA mismatch endonuclease Vsr -
AL346_RS10750 2294733..2295236 - 504 WP_019400648.1 hypothetical protein -
AL346_RS10755 2295276..2295890 - 615 WP_019400647.1 PD-(D/E)XK nuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2211456..2416815 205359


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-264)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-56)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32045.71 Da        Isoelectric Point: 4.9573

>T56423 WP_019400650.1 NZ_CP012398:2293377-2294246 [Chelatococcus sp. CO-6]
MAKEIKNIGASVRARLLNLSKTKGQSFDLVLTRFALERLLFRLSQSPHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSEEAMVAAFRDILAQNVEDGVVFDPDTLRVDRIREELDYGGLRLRAIASVGGARINLTIDIGFGDALEPGAEVVDYPV
MLDLPAPRLRAYARETVIAEKFQAMVALGRANSRMKDFYDIWILSRSFAFDDDRLSRAIAATFARRNTEIPTGLPDALTT
DFAADEQKQRQWKAFIGDVALDPGTLADVIEDLSAFLLPHAAVAAKLTT

Download         Length: 870 bp

>T56423 NZ_CP012398:2293377-2294246 [Chelatococcus sp. CO-6]
ATGGCTAAGGAGATCAAGAATATCGGCGCCTCGGTGCGCGCTCGGCTCCTCAACCTCTCCAAGACGAAGGGACAGAGCTT
CGATCTGGTGCTCACGCGCTTCGCGCTGGAGCGCCTTCTGTTCCGGCTCAGCCAGTCACCCCACGCCGACCGCTTCGTGT
TGAAAGGAGCCATGCTGATGATGAGCTGGTTCGACGATCCGCACCGCGGGACGCGTGATCTCGATCTGCTGGGTTTCGGT
GACCCGAGCGAAGAGGCGATGGTGGCGGCATTCCGGGACATCCTCGCCCAAAACGTTGAAGACGGCGTCGTGTTCGATCC
GGATACCTTGCGTGTCGACCGAATTCGCGAGGAACTCGACTATGGCGGTCTCCGTCTGCGTGCGATCGCTTCGGTCGGCG
GCGCCCGGATCAATCTGACAATCGATATCGGCTTTGGCGATGCGCTGGAGCCTGGGGCGGAAGTCGTCGACTATCCGGTC
ATGCTCGATCTCCCCGCGCCGAGGCTGCGCGCCTACGCGCGGGAGACAGTGATCGCCGAGAAATTCCAGGCGATGGTGGC
GCTGGGCCGGGCGAACAGCCGGATGAAGGACTTCTACGACATCTGGATTCTCAGCCGATCGTTCGCATTCGACGATGACA
GGCTTTCACGCGCGATCGCCGCAACCTTTGCGCGGCGCAATACGGAAATCCCTACCGGCCTGCCTGATGCGCTGACGACC
GACTTTGCGGCTGACGAACAGAAGCAGCGCCAATGGAAGGCGTTCATCGGGGATGTCGCGCTTGATCCTGGAACGCTTGC
GGACGTGATCGAGGACCTGTCTGCTTTTCTTCTGCCTCACGCGGCGGTAGCCGCAAAGCTCACCACATAG

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22208.60 Da        Isoelectric Point: 9.6236

>AT56423 WP_026014859.1 NZ_CP012398:2292767-2293384 [Chelatococcus sp. CO-6]
MPQARSQRETARDLLAARGILRFSELRDAGVTAATVSRMEKDGEVIRLARGLYQLPDAELDANHSLAEAAKRFPKGVICL
VSALAFHGLTDQLPKKVWMAIGRNDWTPKPSDMPIRVLRFSDDLLADSVETHVIEGVSVKVFGVAKTVADCFRHRGKIGL
AVALEGLQEALRQRKSAPAEIARAADTGGVGTVIRPYLEALTANG

Download         Length: 618 bp

>AT56423 NZ_CP012398:2292767-2293384 [Chelatococcus sp. CO-6]
ATGCCTCAGGCCCGATCCCAGCGCGAGACAGCCCGCGATCTCCTCGCGGCGCGTGGGATTCTGCGCTTTTCGGAACTCAG
GGATGCCGGTGTAACCGCCGCAACCGTCAGCCGTATGGAAAAGGATGGCGAGGTCATCCGCCTGGCGCGCGGGCTCTACC
AGCTCCCCGACGCAGAGCTCGACGCAAACCACAGCCTCGCCGAGGCGGCCAAGCGTTTCCCCAAGGGCGTGATCTGCCTC
GTCTCGGCACTCGCCTTTCATGGCCTCACGGATCAGCTTCCGAAGAAGGTGTGGATGGCGATCGGCCGGAACGACTGGAC
GCCGAAGCCGAGCGACATGCCGATCCGTGTGCTGCGTTTCTCGGACGATCTGCTTGCCGACAGCGTTGAAACCCATGTGA
TCGAAGGCGTATCGGTAAAGGTGTTCGGTGTGGCAAAGACCGTCGCGGACTGCTTCCGCCATCGCGGCAAGATCGGTCTT
GCCGTCGCGCTCGAAGGCCTGCAAGAGGCTCTGCGCCAACGAAAATCCGCGCCTGCAGAGATCGCCAGGGCGGCGGATAC
GGGCGGGGTCGGCACGGTGATCCGCCCCTATCTGGAAGCGCTGACCGCCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References