Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
Location | 1056375..1057808 | Replicon | chromosome |
Accession | NZ_CP012387 | ||
Organism | Mycoplasma mycoides subsp. capri strain GM12 |
Toxin (Protein)
Gene name | abiEii | Uniprot ID | - |
Locus tag | AB128_RS04400 | Protein ID | WP_080511208.1 |
Coordinates | 1056375..1057109 (-) | Length | 245 a.a. |
Antitoxin (Protein)
Gene name | abiEi | Uniprot ID | A0A7Z7PN10 |
Locus tag | AB128_RS04405 | Protein ID | WP_020863064.1 |
Coordinates | 1057209..1057808 (-) | Length | 200 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AB128_RS04385 | 1052671..1054248 | - | 1578 | WP_020863062.1 | dicarboxylate/amino acid:cation symporter | - |
AB128_RS04390 | 1054268..1055611 | - | 1344 | WP_023905986.1 | CoA-disulfide reductase | - |
AB128_RS04395 | 1055829..1056329 | + | 501 | WP_020863063.1 | isochorismatase family protein | - |
AB128_RS04400 | 1056375..1057109 | - | 735 | WP_080511208.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
AB128_RS04405 | 1057209..1057808 | - | 600 | WP_020863064.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
AB128_RS04975 | 1058076..1058195 | + | 120 | Protein_836 | isochorismatase family protein | - |
AB128_RS04410 | 1058385..1059719 | + | 1335 | WP_020863065.1 | DUF285 domain-containing protein | - |
AB128_RS05080 | 1059969..1061192 | + | 1224 | WP_020863066.1 | phosphatase PAP2 family protein | - |
AB128_RS04420 | 1061323..1062528 | + | 1206 | WP_020863067.1 | phosphatase PAP2 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 245 a.a. Molecular weight: 28915.65 Da Isoelectric Point: 9.5052
>T56414 WP_080511208.1 NZ_CP012387:c1057109-1056375 [Mycoplasma mycoides subsp. capri]
MKKISKNKDKINIIFKGGFLLSNIIGIKERTTKDIDYLLNNIVFSPDRIKELFEDILDYKKGDKIHFQIQKINEIKKKEK
YTGFRITVECKLDEIVEIIKIDVATGDIITSCQVRYNIENIFHNNSFYVYGYNLETMLAEKIHAIKELSLFNTRTKDFYD
IYLIYNLKRDDIDYMTLKNACINTFKQRNSIFDKDDLLELLNKIKNSQSTHNLTKQKNIYFYNKNIDFKFIIQSIIELIK
NIK
MKKISKNKDKINIIFKGGFLLSNIIGIKERTTKDIDYLLNNIVFSPDRIKELFEDILDYKKGDKIHFQIQKINEIKKKEK
YTGFRITVECKLDEIVEIIKIDVATGDIITSCQVRYNIENIFHNNSFYVYGYNLETMLAEKIHAIKELSLFNTRTKDFYD
IYLIYNLKRDDIDYMTLKNACINTFKQRNSIFDKDDLLELLNKIKNSQSTHNLTKQKNIYFYNKNIDFKFIIQSIIELIK
NIK
Download Length: 735 bp
>T56414 NZ_CP012387:c1057109-1056375 [Mycoplasma mycoides subsp. capri]
CTGAAAAAAATATCTAAGAATAAGGATAAGATAAATATCATATTTAAAGGAGGTTTTTTGCTTTCTAATATAATTGGAAT
AAAAGAAAGAACAACCAAAGATATTGATTATTTATTAAATAACATTGTATTTTCACCTGATCGTATAAAAGAATTATTTG
AAGATATTTTAGATTATAAGAAAGGAGATAAAATACATTTTCAAATTCAAAAAATAAATGAAATTAAGAAAAAAGAAAAA
TATACAGGTTTTAGAATAACTGTAGAATGCAAATTAGATGAAATAGTAGAAATTATAAAAATAGATGTAGCAACAGGTGA
TATCATCACTTCCTGTCAAGTTAGATATAATATTGAAAATATTTTTCATAACAACAGTTTTTATGTTTATGGTTATAACT
TAGAAACTATGTTGGCTGAAAAAATTCATGCAATCAAAGAATTAAGCTTGTTTAATACTAGAACAAAAGATTTCTATGAT
ATATACCTAATTTATAATTTAAAAAGAGATGATATTGACTATATGACGTTGAAAAATGCTTGTATTAATACATTCAAACA
AAGAAACAGCATTTTTGATAAAGACGATTTATTAGAGTTACTCAATAAAATAAAAAATTCGCAATCTACTCATAATTTAT
GAACTAAACAAAAAAATATATATTTTTATAATAAAAACATAGATTTTAAATTTATCATTCAGTCAATTATTGAACTTATT
AAAAACATTAAATAG
CTGAAAAAAATATCTAAGAATAAGGATAAGATAAATATCATATTTAAAGGAGGTTTTTTGCTTTCTAATATAATTGGAAT
AAAAGAAAGAACAACCAAAGATATTGATTATTTATTAAATAACATTGTATTTTCACCTGATCGTATAAAAGAATTATTTG
AAGATATTTTAGATTATAAGAAAGGAGATAAAATACATTTTCAAATTCAAAAAATAAATGAAATTAAGAAAAAAGAAAAA
TATACAGGTTTTAGAATAACTGTAGAATGCAAATTAGATGAAATAGTAGAAATTATAAAAATAGATGTAGCAACAGGTGA
TATCATCACTTCCTGTCAAGTTAGATATAATATTGAAAATATTTTTCATAACAACAGTTTTTATGTTTATGGTTATAACT
TAGAAACTATGTTGGCTGAAAAAATTCATGCAATCAAAGAATTAAGCTTGTTTAATACTAGAACAAAAGATTTCTATGAT
ATATACCTAATTTATAATTTAAAAAGAGATGATATTGACTATATGACGTTGAAAAATGCTTGTATTAATACATTCAAACA
AAGAAACAGCATTTTTGATAAAGACGATTTATTAGAGTTACTCAATAAAATAAAAAATTCGCAATCTACTCATAATTTAT
GAACTAAACAAAAAAATATATATTTTTATAATAAAAACATAGATTTTAAATTTATCATTCAGTCAATTATTGAACTTATT
AAAAACATTAAATAG
Antitoxin
Download Length: 200 a.a. Molecular weight: 23847.67 Da Isoelectric Point: 8.3457
>AT56414 WP_020863064.1 NZ_CP012387:c1057808-1057209 [Mycoplasma mycoides subsp. capri]
MNYVEKIKEKAIQNNGLITRKEIISLKIPPIYITRMVRKKELEKIDIGIYALTSLDNYPYDPEFNFCSRYQVPVFSYVYA
LNLFDFTDVIPLNFEVTVYKGYNAHNLKPNTIVHYVNKEIFNLGITEIRNAFGNWVRTYDIERTICDLIKNRKNINVELF
VKTMNNYVNYEKKDWNKLYEYAEKMHIEKELVEIFQLII
MNYVEKIKEKAIQNNGLITRKEIISLKIPPIYITRMVRKKELEKIDIGIYALTSLDNYPYDPEFNFCSRYQVPVFSYVYA
LNLFDFTDVIPLNFEVTVYKGYNAHNLKPNTIVHYVNKEIFNLGITEIRNAFGNWVRTYDIERTICDLIKNRKNINVELF
VKTMNNYVNYEKKDWNKLYEYAEKMHIEKELVEIFQLII
Download Length: 600 bp
>AT56414 NZ_CP012387:c1057808-1057209 [Mycoplasma mycoides subsp. capri]
ATGAACTATGTAGAAAAAATAAAAGAAAAAGCCATTCAAAATAATGGACTAATAACAAGAAAAGAAATTATAAGTCTAAA
AATCCCACCTATTTATATAACTAGAATGGTAAGAAAAAAAGAACTTGAAAAAATTGATATTGGAATTTATGCACTAACTT
CACTAGATAATTATCCTTACGATCCCGAATTTAATTTTTGTTCAAGATATCAAGTTCCTGTTTTTTCATATGTTTATGCA
TTAAACTTATTTGATTTTACTGATGTTATTCCACTTAATTTTGAAGTAACTGTTTATAAAGGGTATAATGCACATAATCT
TAAACCTAACACAATAGTTCACTATGTTAATAAAGAAATTTTTAATCTAGGAATTACTGAAATTAGAAATGCTTTTGGAA
ATTGGGTAAGAACCTATGATATTGAAAGAACAATTTGTGATCTTATTAAAAATAGAAAAAATATTAATGTTGAACTTTTT
GTAAAAACTATGAATAACTATGTTAATTATGAAAAAAAGGACTGGAATAAACTTTATGAATATGCTGAAAAAATGCACAT
TGAAAAAGAGCTAGTAGAAATATTTCAACTTATTATTTAA
ATGAACTATGTAGAAAAAATAAAAGAAAAAGCCATTCAAAATAATGGACTAATAACAAGAAAAGAAATTATAAGTCTAAA
AATCCCACCTATTTATATAACTAGAATGGTAAGAAAAAAAGAACTTGAAAAAATTGATATTGGAATTTATGCACTAACTT
CACTAGATAATTATCCTTACGATCCCGAATTTAATTTTTGTTCAAGATATCAAGTTCCTGTTTTTTCATATGTTTATGCA
TTAAACTTATTTGATTTTACTGATGTTATTCCACTTAATTTTGAAGTAACTGTTTATAAAGGGTATAATGCACATAATCT
TAAACCTAACACAATAGTTCACTATGTTAATAAAGAAATTTTTAATCTAGGAATTACTGAAATTAGAAATGCTTTTGGAA
ATTGGGTAAGAACCTATGATATTGAAAGAACAATTTGTGATCTTATTAAAAATAGAAAAAATATTAATGTTGAACTTTTT
GTAAAAACTATGAATAACTATGTTAATTATGAAAAAAAGGACTGGAATAAACTTTATGAATATGCTGAAAAAATGCACAT
TGAAAAAGAGCTAGTAGAAATATTTCAACTTATTATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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