Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008428..2008699 Replicon chromosome
Accession NZ_CP012376
Organism Escherichia coli strain GE3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008466..2008569 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008428..2008699 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AKN41_RS09760 2005585..2007024 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AKN41_RS09765 2007142..2007378 + 237 WP_001295499.1 DUF1480 family protein -
AKN41_RS09770 2007483..2007674 + 192 WP_001296140.1 YebW family protein -
AKN41_RS09775 2007675..2008331 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2008428..2008699 + 272 - - Antitoxin
- 2008466..2008569 - 104 - - Toxin
AKN41_RS09780 2008727..2009068 - 342 WP_000976492.1 YebY family protein -
AKN41_RS09785 2009081..2009953 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AKN41_RS09790 2009957..2010331 - 375 WP_000204699.1 CopC domain-containing protein YobA -
AKN41_RS09795 2010470..2010700 + 231 WP_000916763.1 DNA polymerase III subunit theta -
AKN41_RS09800 2010802..2011458 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
AKN41_RS09805 2011482..2012144 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T56337 NZ_CP012376:c2008569-2008466 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT56337 NZ_CP012376:2008428-2008699 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References