Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3835639..3836144 Replicon chromosome
Accession NZ_CP012331
Organism Alcanivorax xenomutans strain P40

Toxin (Protein)


Gene name relB Uniprot ID A0A154C6K4
Locus tag P40_RS17765 Protein ID WP_026949783.1
Coordinates 3835639..3835893 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A154C6W8
Locus tag P40_RS17770 Protein ID WP_026949784.1
Coordinates 3835890..3836144 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P40_RS17740 3831636..3832082 - 447 WP_080531494.1 hypothetical protein -
P40_RS17745 3832406..3832834 - 429 WP_080531495.1 nuclear transport factor 2 family protein -
P40_RS17750 3833050..3833439 + 390 WP_026950066.1 hypothetical protein -
P40_RS17755 3833436..3834932 + 1497 WP_080531496.1 conjugal transfer protein TraG N-terminal domain-containing protein -
P40_RS17760 3835060..3835557 - 498 WP_080531497.1 hypothetical protein -
P40_RS17765 3835639..3835893 - 255 WP_026949783.1 Txe/YoeB family addiction module toxin Toxin
P40_RS17770 3835890..3836144 - 255 WP_026949784.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P40_RS17775 3836248..3836739 - 492 WP_051414508.1 hypothetical protein -
P40_RS17780 3836806..3837222 - 417 WP_080531498.1 MarR family transcriptional regulator -
P40_RS17785 3837316..3837471 - 156 WP_080531944.1 carbon storage regulator -
P40_RS17790 3837583..3838437 - 855 WP_080531499.1 hypothetical protein -
P40_RS17795 3838506..3839807 - 1302 WP_080531500.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10247.87 Da        Isoelectric Point: 9.8631

>T56302 WP_026949783.1 NZ_CP012331:c3835893-3835639 [Alcanivorax xenomutans]
MILSWAEKAWEDYLYWQKVDKKTLKRVNALIKAIQRQPFEGLGDPEPLKHNWSGYWSRRIDREHRLVYKVTEAALIIVQC
RYHY

Download         Length: 255 bp

>T56302 NZ_CP012331:c3835893-3835639 [Alcanivorax xenomutans]
ATGATTCTGTCTTGGGCTGAGAAGGCTTGGGAAGACTATCTGTATTGGCAGAAGGTGGACAAGAAGACCTTGAAACGGGT
CAATGCGCTGATCAAGGCAATACAGCGACAGCCTTTCGAGGGGCTGGGGGATCCCGAGCCATTGAAACACAATTGGTCGG
GGTACTGGTCCCGTCGGATAGATCGGGAGCACCGGCTGGTTTACAAGGTGACGGAGGCGGCACTGATCATTGTTCAATGT
CGTTATCACTACTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9310.54 Da        Isoelectric Point: 4.5680

>AT56302 WP_026949784.1 NZ_CP012331:c3836144-3835890 [Alcanivorax xenomutans]
MDTMSYSAFRARLAGILDKVNDDHKPVLITRQNGKPAVVISLEDFQAYEETAYLMASPKNAQRLNQAIAEVEAGQSLEKG
LIEE

Download         Length: 255 bp

>AT56302 NZ_CP012331:c3836144-3835890 [Alcanivorax xenomutans]
ATGGATACGATGAGCTATTCCGCATTCCGAGCCCGTCTCGCGGGCATCTTGGATAAAGTCAACGATGATCACAAGCCGGT
ACTGATCACCCGGCAAAATGGGAAACCGGCGGTCGTGATCAGTCTGGAGGATTTTCAGGCCTATGAGGAAACGGCGTATT
TGATGGCGAGCCCCAAGAATGCGCAGCGCCTGAACCAAGCCATCGCGGAAGTTGAGGCAGGCCAGAGTCTGGAAAAGGGG
CTGATTGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A154C6K4

Antitoxin

Source ID Structure
AlphaFold DB A0A154C6W8

References