Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1685764..1686425 Replicon chromosome
Accession NZ_CP012331
Organism Alcanivorax xenomutans strain P40

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P40_RS07980 Protein ID WP_080530745.1
Coordinates 1685764..1686186 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P40_RS07985 Protein ID WP_080530746.1
Coordinates 1686183..1686425 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P40_RS07965 1682370..1683128 - 759 WP_080530743.1 class II aldolase/adducin family protein -
P40_RS07970 1683387..1684346 - 960 WP_022994191.1 zinc-binding dehydrogenase -
P40_RS07975 1684510..1685532 + 1023 WP_080530744.1 MBL fold metallo-hydrolase -
P40_RS07980 1685764..1686186 - 423 WP_080530745.1 type II toxin-antitoxin system VapC family toxin Toxin
P40_RS07985 1686183..1686425 - 243 WP_080530746.1 plasmid stabilization protein Antitoxin
P40_RS07990 1686673..1687509 - 837 WP_080530747.1 IclR family transcriptional regulator -
P40_RS07995 1687895..1690027 + 2133 WP_080530748.1 acetate--CoA ligase family protein -
P40_RS08000 1690035..1690877 + 843 WP_022994197.1 MaoC family dehydratase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15454.96 Da        Isoelectric Point: 7.9171

>T56301 WP_080530745.1 NZ_CP012331:c1686186-1685764 [Alcanivorax xenomutans]
MIVLDTNVLSELMRPAPEPRVVAWLDRQPGQDVAVTSITVAEILHGVRRLPAGRRKRRLTDLSIGLFNEEFAGRVLPFDA
PAAAHYAEKLAACEKRGRPVHMADVQIAAICERHGAVLATRNIKDFEPLGVSLLNPWMAD

Download         Length: 423 bp

>T56301 NZ_CP012331:c1686186-1685764 [Alcanivorax xenomutans]
ATGATTGTCCTGGACACCAATGTGCTGTCGGAATTGATGCGGCCGGCACCCGAACCCCGGGTGGTCGCGTGGCTGGACCG
CCAGCCCGGCCAGGATGTGGCGGTTACCAGCATCACCGTGGCGGAAATACTGCATGGCGTCCGCCGCTTGCCCGCCGGGC
GACGCAAACGCCGGCTCACGGACCTGTCCATAGGCTTGTTCAACGAGGAGTTCGCCGGCCGCGTGCTGCCTTTCGACGCC
CCGGCCGCCGCCCACTACGCGGAAAAACTGGCGGCCTGCGAAAAACGCGGACGGCCCGTGCACATGGCCGACGTTCAGAT
CGCCGCCATCTGCGAACGGCACGGCGCTGTACTGGCCACTCGCAATATCAAGGATTTCGAGCCGTTGGGGGTGTCTTTGC
TGAATCCGTGGATGGCCGATTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9166.20 Da        Isoelectric Point: 5.1802

>AT56301 WP_080530746.1 NZ_CP012331:c1686425-1686183 [Alcanivorax xenomutans]
MASITIRNLDDELKARLRLSAAEHGHSMEEEVRQILHRALEPGSDTGLGTRIRERFAAYDAEPPEFERRRDVPRDPGLDQ

Download         Length: 243 bp

>AT56301 NZ_CP012331:c1686425-1686183 [Alcanivorax xenomutans]
ATGGCCTCCATTACCATCCGCAACCTCGATGACGAATTGAAAGCCCGGCTGCGCTTGAGCGCCGCTGAACACGGCCATTC
CATGGAGGAAGAGGTAAGGCAGATCCTGCATCGCGCGCTGGAGCCGGGCTCGGATACCGGTCTTGGCACCCGCATCCGCG
AGCGCTTTGCCGCCTATGATGCTGAACCGCCGGAGTTCGAACGGCGCCGGGACGTGCCCCGCGATCCTGGTCTGGATCAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References