Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 217989..218575 Replicon chromosome
Accession NZ_CP012331
Organism Alcanivorax xenomutans strain P40

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P40_RS01040 Protein ID WP_199466635.1
Coordinates 218207..218575 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P40_RS01035 Protein ID WP_080530188.1
Coordinates 217989..218198 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P40_RS01015 213948..215081 + 1134 WP_167374801.1 CoA transferase -
P40_RS01020 215102..216100 + 999 WP_080530185.1 NADPH:quinone oxidoreductase family protein -
P40_RS01025 216110..216610 + 501 WP_080530186.1 TRAP transporter small permease -
P40_RS01030 216607..217914 + 1308 WP_080530187.1 TRAP transporter large permease subunit -
P40_RS01035 217989..218198 + 210 WP_080530188.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
P40_RS01040 218207..218575 + 369 WP_199466635.1 VapC toxin family PIN domain ribonuclease Toxin
P40_RS01045 218713..219915 - 1203 WP_080530190.1 fatty acid desaturase -
P40_RS01050 219988..221979 - 1992 WP_080531821.1 hydantoinase/oxoprolinase family protein -
P40_RS01055 222168..223112 - 945 WP_080530191.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 200173..218575 18402


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13709.89 Da        Isoelectric Point: 5.1460

>T56298 WP_199466635.1 NZ_CP012331:218207-218575 [Alcanivorax xenomutans]
VDTSVWVAHFREKNEALINLMEMDRALVHPMVLGELACGTPPEPRQRTLGYIGLLRPSNQASLKEVMTFVEQESLYGRGC
GLVDMMLLASTLITPEGRLWTLDKRLAGLADEFDVAYQPHMH

Download         Length: 369 bp

>T56298 NZ_CP012331:218207-218575 [Alcanivorax xenomutans]
GTGGATACCTCGGTATGGGTGGCGCACTTCAGAGAAAAAAATGAGGCGCTGATCAACCTGATGGAAATGGACCGTGCCTT
GGTGCATCCCATGGTCTTGGGCGAGCTTGCCTGTGGGACTCCGCCTGAGCCTCGGCAACGAACTTTGGGCTACATAGGTC
TATTGCGGCCGAGTAATCAGGCCAGCCTTAAGGAGGTCATGACGTTCGTTGAGCAAGAAAGCTTATACGGTCGAGGTTGT
GGTTTGGTGGATATGATGTTGCTCGCTTCAACCCTCATCACTCCCGAAGGGAGGCTTTGGACGTTGGATAAACGCTTGGC
CGGATTGGCGGATGAATTTGACGTGGCGTACCAGCCGCATATGCATTAG

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7756.79 Da        Isoelectric Point: 4.4367

>AT56298 WP_080530188.1 NZ_CP012331:217989-218198 [Alcanivorax xenomutans]
MRTTITIDDALYEQALELAEAGLDKPADILREAIKTYVRVQAARRLAALGGASPDMEDIPRRREEPFQE

Download         Length: 210 bp

>AT56298 NZ_CP012331:217989-218198 [Alcanivorax xenomutans]
ATGCGTACCACAATCACGATTGACGATGCCCTCTACGAGCAGGCATTGGAGCTGGCTGAAGCAGGCTTGGATAAACCCGC
GGATATTCTTCGGGAGGCCATCAAAACCTATGTTCGGGTCCAAGCCGCGCGCCGCCTGGCCGCTTTGGGAGGAGCCTCAC
CTGATATGGAGGATATCCCGCGGCGGCGTGAGGAGCCGTTCCAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References