Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2666508..2666648 Replicon chromosome
Accession NZ_CP012266
Organism Cronobacter dublinensis subsp. dublinensis LMG 23823

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2666510..2666613 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2666508..2666648 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AFK67_RS12145 2662179..2662931 + 753 WP_007734232.1 hypothetical protein -
AFK67_RS12150 2662936..2663595 + 660 Protein_2419 DNA methyltransferase -
AFK67_RS12155 2663592..2663810 + 219 WP_032967691.1 hypothetical protein -
AFK67_RS22875 2664369..2664563 - 195 WP_134792954.1 hypothetical protein -
AFK67_RS12165 2665106..2665378 + 273 WP_032967689.1 excisionase -
AFK67_RS12170 2665347..2666432 + 1086 WP_038883315.1 phage integrase Arm DNA-binding domain-containing protein -
- 2666508..2666648 + 141 - - Antitoxin
- 2666510..2666613 - 104 - - Toxin
AFK67_RS12175 2666752..2667090 - 339 WP_007698868.1 YebY family protein -
AFK67_RS12180 2667105..2667974 - 870 WP_032967688.1 copper homeostasis membrane protein CopD -
AFK67_RS12185 2667979..2668353 - 375 WP_007734211.1 CopC domain-containing protein YobA -
AFK67_RS12190 2668500..2668730 + 231 WP_007734209.1 DNA polymerase III subunit theta -
AFK67_RS12195 2668806..2669468 + 663 WP_007734207.1 exodeoxyribonuclease X -
AFK67_RS12200 2669465..2671528 - 2064 WP_032967687.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2619762..2687941 68179


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T56197 NZ_CP012266:c2666613-2666510 [Cronobacter dublinensis subsp. dublinensis LMG 23823]
GGCAAGGCGACTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTATCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT56197 NZ_CP012266:2666508-2666648 [Cronobacter dublinensis subsp. dublinensis LMG 23823]
ATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGATAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTCAGTCGCCTTGCCATTTAAGAATAGATGACGACAGCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References