Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) virAT/YafQ(toxin)
Location 1670996..1671539 Replicon chromosome
Accession NZ_CP012215
Organism Campylobacter jejuni strain CJ518CC45

Toxin (Protein)


Gene name virT Uniprot ID -
Locus tag AEI13_RS08780 Protein ID WP_053868684.1
Coordinates 1670996..1671265 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID A0A5T1CFM5
Locus tag AEI13_RS08785 Protein ID WP_053868685.1
Coordinates 1671255..1671539 (-) Length 95 a.a.

Genomic Context

AEI13_RS08770AEI13_RS08760AEI13_RS08765AEI13_RS08775AEI13_RS08780AEI13_RS08785AEI13_RS08790AEI13_RS08795AEI13_RS08800AEI13_RS08805AEI13_RS08810AEI13_RS08815AEI13_RS08820AEI13_RS08825
Location: 1668865..1670448 (1584 bp)
Type: Others
Protein ID: WP_260535762.1
Location: 1667444..1667686 (243 bp)
Type: Others
Protein ID: WP_011117593.1
Location: 1667686..1667991 (306 bp)
Type: Others
Protein ID: WP_014517469.1
Location: 1670571..1670882 (312 bp)
Type: Others
Protein ID: Protein_1710
Location: 1670996..1671265 (270 bp)
Type: Toxin
Protein ID: WP_053868684.1
Location: 1671255..1671539 (285 bp)
Type: Antitoxin
Protein ID: WP_053868685.1
Location: 1671763..1672125 (363 bp)
Type: Others
Protein ID: WP_025443372.1
Location: 1672298..1672600 (303 bp)
Type: Others
Protein ID: WP_053868731.1
Location: 1672600..1673031 (432 bp)
Type: Others
Protein ID: WP_025443374.1
Location: 1673028..1673444 (417 bp)
Type: Others
Protein ID: WP_115784918.1
Location: 1673980..1674198 (219 bp)
Type: Others
Protein ID: WP_025443376.1
Location: 1674210..1674515 (306 bp)
Type: Others
Protein ID: WP_025443377.1
Location: 1674529..1674873 (345 bp)
Type: Others
Protein ID: WP_011117579.1
Location: 1675334..1675759 (426 bp)
Type: Others
Protein ID: WP_052835067.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AEI13_RS08760 (AEI13_08790)1667444..1667686-243WP_011117593.1hypothetical protein-
AEI13_RS08765 (AEI13_08795)1667686..1667991-306WP_014517469.1hypothetical protein-
AEI13_RS08770 (AEI13_08800)1668865..1670448+1584WP_260535762.1relaxase/mobilization nuclease domain-containing protein-
AEI13_RS08775 (AEI13_08805)1670571..1670882-312Protein_1710hypothetical protein-
AEI13_RS08780 (AEI13_08810)1670996..1671265-270WP_053868684.1type II toxin-antitoxin system YafQ family toxinToxin
AEI13_RS08785 (AEI13_08815)1671255..1671539-285WP_053868685.1hypothetical proteinAntitoxin
AEI13_RS08790 (AEI13_08820)1671763..1672125-363WP_025443372.1hypothetical protein-
AEI13_RS08795 (AEI13_08825)1672298..1672600-303WP_053868731.1hypothetical protein-
AEI13_RS08800 (AEI13_08830)1672600..1673031-432WP_025443374.1hypothetical protein-
AEI13_RS08805 (AEI13_08835)1673028..1673444-417WP_115784918.1hypothetical protein-
AEI13_RS08810 (AEI13_08845)1673980..1674198-219WP_025443376.1hypothetical protein-
AEI13_RS08815 (AEI13_08850)1674210..1674515-306WP_025443377.1hypothetical protein-
AEI13_RS08820 (AEI13_08855)1674529..1674873-345WP_011117579.1hypothetical protein-
AEI13_RS08825 (AEI13_08860)1675334..1675759-426WP_052835067.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10616.28 Da        Isoelectric Point: 9.5064

>T56125 WP_053868684.1 NZ_CP012215:c1671265-1670996 [Campylobacter jejuni]
MPYKITLSKKYKQKYKKANTKDRILIDEVVEKLSNDETLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELYLA
NLGNHNNIF

Download         Length: 270 bp

>T56125 NZ_CP012215:c1671265-1670996 [Campylobacter jejuni]
ATGCCTTATAAAATTACATTATCTAAAAAATACAAGCAAAAATATAAAAAAGCAAACACAAAAGACAGAATATTGATTGA
TGAAGTTGTTGAAAAATTATCTAATGATGAAACATTAGAAGAAAAATACAAAGACCACGCATTAAAAGGAAATTATATTG
GTTTTAGAGAATGCCACATTAAACCTGATTTGTTATTAGTCTATCGCAAAAATAATGATATTTTAGAATTATATTTGGCT
AATTTAGGAAATCACAATAATATTTTTTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11186.76 Da        Isoelectric Point: 10.0400

>AT56125 WP_053868685.1 NZ_CP012215:c1671539-1671255 [Campylobacter jejuni]
MFDYSKYENASKKQLIHALTLAEKRAEKLNSQLKENNEFFKFLQKKLKKSFNAKKTKKAEQRRPELDEAIEDYKNGNVET
YANFEEYKKAMNAL

Download         Length: 285 bp

>AT56125 NZ_CP012215:c1671539-1671255 [Campylobacter jejuni]
ATGTTTGATTATTCTAAATATGAAAATGCTAGCAAAAAACAATTAATACACGCTTTGACTTTAGCAGAAAAAAGGGCGGA
GAAACTAAACTCGCAATTAAAAGAGAATAACGAATTTTTTAAATTTTTACAAAAAAAGTTAAAAAAATCTTTTAACGCCA
AAAAAACAAAAAAAGCAGAGCAAAGAAGACCTGAATTAGATGAAGCGATTGAAGATTATAAAAATGGAAATGTAGAAACC
TATGCTAATTTTGAAGAATATAAAAAGGCTATGAATGCCTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5T1CFM5

References