Detailed information of TA system TA056124

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virAT/YafQ(toxin)
• Location: 1700934..1701477
• Replicon: chromosome
• Accession: NZ_CP012206
• Organism: Campylobacter jejuni strain CJ067CC45

Toxin (Protein)

• Gene name: virT
• Uniprot ID: -
• Locus tag: AEI02_RS08940
• Protein ID: WP_053868684.1
• Coordinates: 1700934..1701203 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: virA
• Uniprot ID: A0A5T1CFM5
• Locus tag: AEI02_RS08945
• Protein ID: WP_053868685.1
• Coordinates: 1701193..1701477 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AEI02_RS08915	1697209..1697451	-	243	WP_011117593.1	hypothetical protein	-
AEI02_RS08920	1697451..1697756	-	306	WP_014517469.1	hypothetical protein	-
AEI02_RS08930	1698630..1700201	+	1572	WP_053868683.1	relaxase/mobilization nuclease domain-containing protein	-
AEI02_RS08935	1700428..1700820	-	393	WP_014517466.1	hypothetical protein	-
AEI02_RS08940	1700934..1701203	-	270	WP_053868684.1	type II toxin-antitoxin system YafQ family toxin	Toxin
AEI02_RS08945	1701193..1701477	-	285	WP_053868685.1	hypothetical protein	Antitoxin
AEI02_RS08950	1701701..1702063	-	363	WP_025443372.1	hypothetical protein	-
AEI02_RS08955	1702263..1702598	-	336	WP_011117586.1	hypothetical protein	-
AEI02_RS08960	1702663..1703028	-	366	WP_053868732.1	hypothetical protein	-
AEI02_RS08965	1703195..1703497	-	303	WP_053868731.1	hypothetical protein	-
AEI02_RS08970	1703497..1703928	-	432	WP_025443374.1	hypothetical protein	-
AEI02_RS08975	1703925..1704341	-	417	WP_115784918.1	hypothetical protein	-
AEI02_RS08985	1704877..1705095	-	219	WP_025443376.1	hypothetical protein	-
AEI02_RS08990	1705107..1705412	-	306	WP_025443377.1	hypothetical protein	-
AEI02_RS08995	1705426..1705770	-	345	WP_011117579.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10616.28 Da
• Isoelectric Point: 9.5064

>T56124 WP_053868684.1 NZ_CP012206:c1701203-1700934 [Campylobacter jejuni]
MPYKITLSKKYKQKYKKANTKDRILIDEVVEKLSNDETLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELYLA
NLGNHNNIF

Nucleotide

• Length: 270 bp

>T56124 NZ_CP012206:c1701203-1700934 [Campylobacter jejuni]
ATGCCTTATAAAATTACATTATCTAAAAAATACAAGCAAAAATATAAAAAAGCAAACACAAAAGACAGAATATTGATTGA
TGAAGTTGTTGAAAAATTATCTAATGATGAAACATTAGAAGAAAAATACAAAGACCACGCATTAAAAGGAAATTATATTG
GTTTTAGAGAATGCCACATTAAACCTGATTTGTTATTAGTCTATCGCAAAAATAATGATATTTTAGAATTATATTTGGCT
AATTTAGGAAATCACAATAATATTTTTTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11186.76 Da
• Isoelectric Point: 10.0400

>AT56124 WP_053868685.1 NZ_CP012206:c1701477-1701193 [Campylobacter jejuni]
MFDYSKYENASKKQLIHALTLAEKRAEKLNSQLKENNEFFKFLQKKLKKSFNAKKTKKAEQRRPELDEAIEDYKNGNVET
YANFEEYKKAMNAL

Nucleotide

• Length: 285 bp

>AT56124 NZ_CP012206:c1701477-1701193 [Campylobacter jejuni]
ATGTTTGATTATTCTAAATATGAAAATGCTAGCAAAAAACAATTAATACACGCTTTGACTTTAGCAGAAAAAAGGGCGGA
GAAACTAAACTCGCAATTAAAAGAGAATAACGAATTTTTTAAATTTTTACAAAAAAAGTTAAAAAAATCTTTTAACGCCA
AAAAAACAAAAAAAGCAGAGCAAAGAAGACCTGAATTAGATGAAGCGATTGAAGATTATAAAAATGGAAATGTAGAAACC
TATGCTAATTTTGAAGAATATAAAAAGGCTATGAATGCCTTATAA

Structures

Antitoxin

• AlphaFold DB: A0A5T1CFM5