56122

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3326281..3327992 Replicon chromosome
Accession NZ_CP012202
Organism Alteromonas macleodii strain HOT1A3

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag ACZ81_RS14450 Protein ID WP_061486364.1
Coordinates 3326281..3326928 (+) Length 216 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag ACZ81_RS14455 Protein ID WP_061486365.1
Coordinates 3326928..3327992 (+) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACZ81_RS14435 3322336..3323847 + 1512 WP_061486361.1 serine hydrolase -
ACZ81_RS14440 3324288..3325073 - 786 WP_061486362.1 hypothetical protein -
ACZ81_RS14445 3325704..3326279 + 576 WP_061486363.1 DUF4433 domain-containing protein -
ACZ81_RS14450 3326281..3326928 + 648 WP_061486364.1 DUF4433 domain-containing protein Toxin
ACZ81_RS14455 3326928..3327992 + 1065 WP_061486365.1 macro domain-containing protein Antitoxin
ACZ81_RS14460 3328354..3331251 - 2898 WP_061486366.1 aminomethyl-transferring glycine dehydrogenase -
ACZ81_RS14465 3331373..3331762 - 390 WP_014950360.1 glycine cleavage system protein GcvH -
ACZ81_RS14470 3331789..3332868 - 1080 WP_061486367.1 glycine cleavage system aminomethyltransferase GcvT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-215)

Antitoxin

Macro domain

(18-128)


Sequences

Toxin        


Download         Length: 216 a.a.        Molecular weight: 25120.63 Da        Isoelectric Point: 7.4767

>T56122 WP_061486364.1 NZ_CP012202:3326281-3326928 [Alteromonas macleodii]
MYNYCQTLNPQKALIWRIVHRNNIPWILDNGLYCGNSHVQSPNWEAIGNSELIQKRATHPVPISPFGSLNDYVPFYFTPF
SPMLLNIKSGRGVKQRANEDIVILVSSLHKVEQLNLDFVYTDMHAYYQWASFYSDLNHLGEVDWPILQTRNFARDLNDPA
KFERYQAEALVKQHCPINALVGIACYNTRVEQELKHHIQQRNMNLDVIVRPGWYF

Download         Length: 648 bp

>T56122 NZ_CP012202:3326281-3326928 [Alteromonas macleodii]
TTGTATAACTATTGTCAAACCCTCAATCCACAAAAAGCTCTGATTTGGCGTATCGTGCATCGCAATAATATCCCGTGGAT
ATTAGATAATGGTCTTTATTGTGGTAATAGCCATGTCCAGTCACCTAATTGGGAGGCCATAGGTAATTCGGAACTCATAC
AGAAACGCGCCACTCACCCAGTCCCCATATCACCATTTGGCTCTTTAAATGACTATGTGCCTTTCTATTTTACCCCGTTT
TCCCCCATGTTGCTCAATATCAAGTCTGGACGGGGGGTTAAGCAGAGGGCTAACGAAGATATCGTTATATTGGTATCATC
ATTACACAAAGTTGAACAACTAAACTTAGATTTTGTCTATACGGACATGCATGCATATTATCAGTGGGCGAGTTTTTACT
CGGATTTGAATCACTTGGGTGAAGTAGATTGGCCTATATTACAAACGCGGAATTTTGCCAGAGATCTCAACGACCCAGCC
AAGTTTGAACGATATCAAGCAGAAGCATTGGTAAAGCAGCATTGTCCAATAAATGCTTTAGTAGGTATAGCTTGTTACAA
TACTCGAGTTGAACAAGAGTTAAAACATCATATTCAACAGCGCAATATGAATTTAGACGTAATTGTACGTCCAGGATGGT
ACTTCTAA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 40015.25 Da        Isoelectric Point: 8.0792

>AT56122 WP_061486365.1 NZ_CP012202:3326928-3327992 [Alteromonas macleodii]
MITYTQGNLLEAQVEALVNTVNTVGVMGKGIALMFKERFPKNMAEYASACKAKQVNTGKMFVTETSELMGPKWIVNFPTK
QHWRAKSKMEWIQEGLIDLRYFLENNNVRSIAIPPLGAGQGGLAWPDVKMEIEKALSDIKTTNIIVFEPTSKYQNVAKAS
GVKKLTPARALVAELVRRYWILGMECSLLEIQKLAWFLQRTIEKRGLKNELKLKFEANYYGPYANNLDHLLNALDGSYLK
SDKRIPDCDPLDVIWFNESEKQKISTYLNTEAKEYLPALEGATQVISGFESPFGLELLSTVDWLVTNQGCERTVESIKEG
IANWPAGAKWAQRKFNLFSNKDIEFALTNLEILA

Download         Length: 1065 bp

>AT56122 NZ_CP012202:3326928-3327992 [Alteromonas macleodii]
ATGATCACTTATACGCAAGGTAATTTACTCGAAGCACAAGTAGAGGCACTCGTTAACACTGTAAATACAGTTGGAGTTAT
GGGGAAAGGTATTGCACTAATGTTCAAAGAGCGCTTTCCCAAAAACATGGCTGAATATGCTAGTGCTTGCAAAGCTAAGC
AGGTAAATACAGGTAAAATGTTTGTTACTGAAACTAGTGAGTTGATGGGTCCTAAGTGGATTGTTAATTTTCCTACTAAG
CAGCATTGGCGTGCAAAATCTAAAATGGAGTGGATCCAAGAGGGCTTAATCGATCTTCGATATTTCTTAGAAAACAACAA
TGTCCGATCAATAGCTATTCCGCCACTTGGTGCGGGACAGGGTGGACTAGCCTGGCCAGATGTAAAAATGGAGATCGAAA
AGGCTTTATCAGACATTAAAACCACAAATATTATTGTGTTTGAGCCTACCAGTAAATATCAAAACGTGGCCAAGGCATCA
GGTGTTAAGAAACTTACTCCAGCGCGAGCATTAGTTGCAGAATTAGTGAGGCGCTATTGGATTTTGGGTATGGAATGTAG
TTTGTTGGAGATTCAAAAACTCGCTTGGTTTTTACAAAGAACAATCGAAAAAAGAGGGTTAAAAAACGAATTAAAACTGA
AATTTGAAGCAAATTATTATGGACCATATGCCAATAATCTAGACCATTTACTAAATGCTCTAGATGGTAGTTATTTGAAA
TCTGATAAACGAATTCCTGATTGCGACCCGTTGGATGTGATTTGGTTTAATGAATCAGAAAAGCAAAAAATTTCAACGTA
CTTGAATACAGAAGCCAAAGAATATTTACCCGCACTCGAGGGCGCAACTCAAGTAATCAGCGGTTTCGAATCCCCTTTTG
GTTTAGAGCTTCTATCTACAGTAGATTGGTTAGTTACTAACCAAGGCTGTGAAAGGACTGTTGAATCTATTAAAGAAGGT
ATAGCTAATTGGCCTGCTGGAGCTAAATGGGCGCAAAGAAAATTTAACTTATTTAGCAATAAAGATATTGAATTTGCTTT
AACTAATTTGGAAATTCTAGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References