Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 4614475..4615006 Replicon chromosome
Accession NZ_CP012201
Organism Massilia sp. NR 4-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ACZ75_RS27730 Protein ID WP_082219620.1
Coordinates 4614475..4614693 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ACZ75_RS27735 Protein ID WP_082219621.1
Coordinates 4614740..4615006 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACZ75_RS19175 4609611..4610909 - 1299 WP_050410482.1 FAD-dependent oxidoreductase -
ACZ75_RS19180 4611439..4612104 - 666 WP_050412593.1 NUDIX hydrolase -
ACZ75_RS19185 4612222..4613367 + 1146 WP_050412594.1 hypothetical protein -
ACZ75_RS19190 4613360..4614484 + 1125 WP_050410484.1 hypothetical protein -
ACZ75_RS27730 4614475..4614693 - 219 WP_082219620.1 Txe/YoeB family addiction module toxin Toxin
ACZ75_RS27735 4614740..4615006 - 267 WP_082219621.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ACZ75_RS19195 4615079..4616380 - 1302 WP_050410486.1 transcriptional regulator PtsJ -
ACZ75_RS19200 4616456..4617268 + 813 WP_050410487.1 YggS family pyridoxal phosphate-dependent enzyme -
ACZ75_RS19205 4617278..4617994 + 717 WP_050410489.1 type 1 glutamine amidotransferase -
ACZ75_RS19210 4618059..4618937 + 879 WP_150119165.1 AraC family transcriptional regulator -
ACZ75_RS19215 4618981..4619949 + 969 WP_050412595.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-71)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8444.75 Da        Isoelectric Point: 9.8463

>T56119 WP_082219620.1 NZ_CP012201:c4614693-4614475 [Massilia sp. NR 4-1]
IYWQGQDKKTLKRINELIKAAGRTPFEGIGKPEPLKGNLTGLWSRRIDERNRLVYEVTAQELVIIACRYHYE

Download         Length: 219 bp

>T56119 NZ_CP012201:c4614693-4614475 [Massilia sp. NR 4-1]
ATTTACTGGCAGGGCCAGGATAAAAAAACCTTGAAACGCATCAATGAGCTGATCAAAGCCGCAGGCAGAACACCTTTCGA
AGGTATCGGCAAACCCGAACCTTTGAAAGGCAACCTGACCGGGCTTTGGTCACGCAGGATCGATGAGCGCAATCGGCTGG
TATATGAAGTCACCGCACAGGAATTGGTCATCATCGCCTGCCGATATCACTATGAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9596.86 Da        Isoelectric Point: 6.2149

>AT56119 WP_082219621.1 NZ_CP012201:c4615006-4614740 [Massilia sp. NR 4-1]
MRIINFSDARSNLRSVIDQVVEDADVTVISRRDAPDAVLMSFEHYSSLIETVHLLSSPANAAHLAKSIAQARAGKAQPRK
LIEPADAE

Download         Length: 267 bp

>AT56119 NZ_CP012201:c4615006-4614740 [Massilia sp. NR 4-1]
ATGAGAATCATCAATTTCTCCGATGCTCGCAGCAACCTGCGATCAGTGATCGATCAGGTGGTGGAAGACGCAGATGTAAC
GGTTATCTCACGGCGCGATGCGCCGGATGCGGTATTGATGTCCTTTGAGCACTACAGCAGTCTGATAGAAACCGTTCATT
TATTAAGCTCGCCAGCAAATGCCGCCCATCTGGCGAAGTCGATAGCCCAAGCCCGAGCCGGAAAAGCACAGCCCAGAAAG
CTTATCGAGCCAGCCGACGCCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References