56106

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6241090..6241609 Replicon chromosome
Accession NZ_CP012179
Organism Pseudomonas syringae pv. actinidiae ICMP 18708

Toxin (Protein)


Gene name relE Uniprot ID S6W9N2
Locus tag NZ708_RS28020 Protein ID WP_017684310.1
Coordinates 6241090..6241380 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag NZ708_RS28025 Protein ID WP_002551444.1
Coordinates 6241370..6241609 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZ708_RS27995 6237420..6237962 + 543 WP_017684306.1 hypothetical protein -
NZ708_RS32760 6238026..6238309 - 284 Protein_5500 type II toxin-antitoxin system RelE/ParE family toxin -
NZ708_RS28000 6238299..6238541 - 243 WP_017684307.1 hypothetical protein -
NZ708_RS28005 6238722..6239336 - 615 WP_017684308.1 histidine phosphatase family protein -
NZ708_RS28010 6239429..6239770 - 342 WP_003380754.1 hypothetical protein -
NZ708_RS28015 6240127..6240864 + 738 WP_017684309.1 hypothetical protein -
NZ708_RS28020 6241090..6241380 - 291 WP_017684310.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NZ708_RS28025 6241370..6241609 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NZ708_RS28030 6241785..6242246 - 462 WP_017684311.1 GNAT family N-acetyltransferase -
NZ708_RS28035 6242333..6242902 - 570 WP_017684312.1 GNAT family N-acetyltransferase -
NZ708_RS28040 6243063..6243557 + 495 WP_005621707.1 hypothetical protein -
NZ708_RS28045 6243830..6244177 + 348 WP_017684314.1 helix-turn-helix domain-containing protein -
NZ708_RS28050 6244263..6245537 - 1275 WP_003380766.1 OprD family porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11145.98 Da        Isoelectric Point: 10.0984

>T56106 WP_017684310.1 NZ_CP012179:c6241380-6241090 [Pseudomonas syringae pv. actinidiae ICMP 18708]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG

Download         Length: 291 bp

>T56106 NZ_CP012179:c6241380-6241090 [Pseudomonas syringae pv. actinidiae ICMP 18708]
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT56106 WP_002551444.1 NZ_CP012179:c6241609-6241370 [Pseudomonas syringae pv. actinidiae ICMP 18708]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT56106 NZ_CP012179:c6241609-6241370 [Pseudomonas syringae pv. actinidiae ICMP 18708]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAGGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACCCC
TTCGGAACTGCTGCGCCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGTTGCCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCCTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M1I3

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References