Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 5170401..5170942 | Replicon | chromosome |
Accession | NZ_CP012179 | ||
Organism | Pseudomonas syringae pv. actinidiae ICMP 18708 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0K8LVV5 |
Locus tag | NZ708_RS23260 | Protein ID | WP_017683357.1 |
Coordinates | 5170667..5170942 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A0K8LU58 |
Locus tag | NZ708_RS23255 | Protein ID | WP_003382249.1 |
Coordinates | 5170401..5170667 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NZ708_RS23240 | 5165684..5165947 | + | 264 | WP_017683360.1 | hypothetical protein | - |
NZ708_RS23245 | 5166075..5167955 | - | 1881 | WP_003382247.1 | methyl-accepting chemotaxis protein | - |
NZ708_RS23250 | 5168314..5170236 | + | 1923 | WP_017683359.1 | methyl-accepting chemotaxis protein | - |
NZ708_RS23255 | 5170401..5170667 | + | 267 | WP_003382249.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
NZ708_RS23260 | 5170667..5170942 | + | 276 | WP_017683357.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
NZ708_RS23265 | 5171514..5172782 | + | 1269 | WP_007244158.1 | OprD family porin | - |
NZ708_RS23270 | 5172961..5173785 | + | 825 | WP_003380380.1 | NAD(P)-dependent oxidoreductase | - |
NZ708_RS23275 | 5173845..5174729 | + | 885 | WP_003380378.1 | SMP-30/gluconolactonase/LRE family protein | - |
NZ708_RS23280 | 5174786..5175825 | + | 1040 | Protein_4563 | TRAP transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10770.41 Da Isoelectric Point: 7.0123
>T56104 WP_017683357.1 NZ_CP012179:5170667-5170942 [Pseudomonas syringae pv. actinidiae ICMP 18708]
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR
Download Length: 276 bp
>T56104 NZ_CP012179:5170667-5170942 [Pseudomonas syringae pv. actinidiae ICMP 18708]
ATGGAGCTGATGTGGACAAGCAAAACGCTATCTGACGTCACCCGCCTGTATGATTTTTTAGCGGTAGCAAACCAGCCCGC
TGCCGCCCAGACCGCACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCGCGGATTGGTGAGCGTCTGGAGG
AGTTTGAGCCCCGGGATGTGCGCAGAATTCAGATAGGCCGCTATGAAATGCGCTACGAAATTGTGGACTCAACAATTTAT
CTGTTGCGGCTGTGGCATACACGCGAGGATCGGTAA
ATGGAGCTGATGTGGACAAGCAAAACGCTATCTGACGTCACCCGCCTGTATGATTTTTTAGCGGTAGCAAACCAGCCCGC
TGCCGCCCAGACCGCACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCGCGGATTGGTGAGCGTCTGGAGG
AGTTTGAGCCCCGGGATGTGCGCAGAATTCAGATAGGCCGCTATGAAATGCGCTACGAAATTGTGGACTCAACAATTTAT
CTGTTGCGGCTGTGGCATACACGCGAGGATCGGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 9934.24 Da Isoelectric Point: 5.7066
>AT56104 WP_003382249.1 NZ_CP012179:5170401-5170667 [Pseudomonas syringae pv. actinidiae ICMP 18708]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR
Download Length: 267 bp
>AT56104 NZ_CP012179:5170401-5170667 [Pseudomonas syringae pv. actinidiae ICMP 18708]
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCGTGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACACCTCTGCCGGTTCCGCGCTGA
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCGTGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACACCTCTGCCGGTTCCGCGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8LVV5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8LU58 |