Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4497197..4497560 Replicon chromosome
Accession NZ_CP012146
Organism Xanthomonas campestris pv. campestris strain ICMP 4013

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag AEA01_RS19290 Protein ID WP_011270059.1
Coordinates 4497197..4497331 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag AEA01_RS19295 Protein ID WP_011038999.1
Coordinates 4497408..4497560 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AEA01_RS19270 4492461..4494113 - 1653 WP_050912502.1 M28 family peptidase -
AEA01_RS19275 4494278..4495222 - 945 WP_043877842.1 MBL fold metallo-hydrolase -
AEA01_RS19280 4495306..4496595 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
AEA01_RS19285 4496755..4496964 - 210 WP_011038998.1 CsbD family protein -
AEA01_RS19290 4497197..4497331 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
AEA01_RS19295 4497408..4497560 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
AEA01_RS19300 4497671..4498594 - 924 Protein_3782 arginase -
AEA01_RS19305 4498908..4499369 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
AEA01_RS19310 4499452..4499811 + 360 WP_011039002.1 hypothetical protein -
AEA01_RS19315 4499914..4500831 + 918 WP_011039003.1 hypothetical protein -
AEA01_RS19320 4500828..4501370 + 543 WP_011039004.1 GTPase -
AEA01_RS19325 4501705..4502388 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T56028 WP_011270059.1 NZ_CP012146:c4497331-4497197 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T56028 NZ_CP012146:c4497331-4497197 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT56028 WP_011038999.1 NZ_CP012146:c4497560-4497408 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT56028 NZ_CP012146:c4497560-4497408 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References