Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1935779..1936013 | Replicon | chromosome |
| Accession | NZ_CP012137 | ||
| Organism | Shigella flexneri 2a strain 981 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1935780..1935883 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1935779..1936013 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AD867_RS10550 | 1931225..1931692 | - | 468 | Protein_1943 | DNA-binding transcriptional regulator PgrR | - |
| AD867_RS10555 | 1931756..1932066 | + | 311 | Protein_1944 | transposase | - |
| AD867_RS27630 | 1932109..1933304 | - | 1196 | Protein_1945 | IS3 family transposase | - |
| AD867_RS10575 | 1933359..1934207 | + | 849 | Protein_1946 | IS3-like element IS600 family transposase | - |
| AD867_RS27635 | 1934324..1934605 | + | 282 | WP_005127484.1 | excisionase | - |
| AD867_RS31350 | 1934571..1935648 | + | 1078 | Protein_1948 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1935779..1936013 | + | 235 | - | - | Antitoxin |
| - | 1935780..1935883 | - | 104 | - | - | Toxin |
| AD867_RS10590 | 1936041..1936382 | - | 342 | WP_000976476.1 | YebY family protein | - |
| AD867_RS27650 | 1936395..1937267 | - | 873 | Protein_1950 | copper homeostasis membrane protein CopD | - |
| AD867_RS10605 | 1937271..1937645 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| AD867_RS10610 | 1937784..1938014 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| AD867_RS10615 | 1938116..1938772 | + | 657 | Protein_1953 | carbon-nitrogen hydrolase family protein YobB | - |
| AD867_RS10620 | 1938796..1939458 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T55976 NZ_CP012137:c1935883-1935780 [Shigella flexneri 2a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT55976 NZ_CP012137:1935779-1936013 [Shigella flexneri 2a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
