Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
| Location | 639358..639911 | Replicon | chromosome |
| Accession | NZ_CP012096 | ||
| Organism | Serratia plymuthica strain 3Rp8 | ||
Toxin (Protein)
| Gene name | ccdB | Uniprot ID | S4YH80 |
| Locus tag | ADP72_RS03040 | Protein ID | WP_020438747.1 |
| Coordinates | 639358..639672 (-) | Length | 105 a.a. |
Antitoxin (Protein)
| Gene name | ccdA | Uniprot ID | S4YG56 |
| Locus tag | ADP72_RS03045 | Protein ID | WP_020438746.1 |
| Coordinates | 639675..639911 (-) | Length | 79 a.a. |
Genomic Context
Location: 636391..637308 (918 bp)
Type: Others
Protein ID: WP_004942342.1
Type: Others
Protein ID: WP_004942342.1
Location: 637337..638464 (1128 bp)
Type: Others
Protein ID: WP_004942340.1
Type: Others
Protein ID: WP_004942340.1
Location: 638479..639324 (846 bp)
Type: Others
Protein ID: WP_006324390.1
Type: Others
Protein ID: WP_006324390.1
Location: 635126..636283 (1158 bp)
Type: Others
Protein ID: WP_064799408.1
Type: Others
Protein ID: WP_064799408.1
Location: 639358..639672 (315 bp)
Type: Toxin
Protein ID: WP_020438747.1
Type: Toxin
Protein ID: WP_020438747.1
Location: 639675..639911 (237 bp)
Type: Antitoxin
Protein ID: WP_020438746.1
Type: Antitoxin
Protein ID: WP_020438746.1
Location: 640056..640964 (909 bp)
Type: Others
Protein ID: WP_004942335.1
Type: Others
Protein ID: WP_004942335.1
Location: 640974..641894 (921 bp)
Type: Others
Protein ID: WP_006324386.1
Type: Others
Protein ID: WP_006324386.1
Location: 641947..643485 (1539 bp)
Type: Others
Protein ID: WP_064799409.1
Type: Others
Protein ID: WP_064799409.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ADP72_RS03020 | 635126..636283 | - | 1158 | WP_064799408.1 | YbfB/YjiJ family MFS transporter | - |
| ADP72_RS03025 | 636391..637308 | + | 918 | WP_004942342.1 | LysR family transcriptional regulator | - |
| ADP72_RS03030 | 637337..638464 | + | 1128 | WP_004942340.1 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase | - |
| ADP72_RS03035 | 638479..639324 | + | 846 | WP_006324390.1 | S-formylglutathione hydrolase | - |
| ADP72_RS03040 | 639358..639672 | - | 315 | WP_020438747.1 | CcdB family protein | Toxin |
| ADP72_RS03045 | 639675..639911 | - | 237 | WP_020438746.1 | type II toxin-antitoxin system CcdA family antitoxin | Antitoxin |
| ADP72_RS03050 | 640056..640964 | - | 909 | WP_004942335.1 | glutathione ABC transporter permease GsiD | - |
| ADP72_RS03055 | 640974..641894 | - | 921 | WP_006324386.1 | glutathione ABC transporter permease GsiC | - |
| ADP72_RS03060 | 641947..643485 | - | 1539 | WP_064799409.1 | glutathione ABC transporter substrate-binding protein GsiB | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 105 a.a. Molecular weight: 11685.58 Da Isoelectric Point: 5.8036
>T55761 WP_020438747.1 NZ_CP012096:c639672-639358 [Serratia plymuthica]
MQFTVYANTGKSAVYPLLLDVTSDIIGQLNRRVVIPLLPIEKYPASTRPERLNPLVRLVDDNEYAVMTHEMASIPVRILG
AEFCDASQYRTKVKAAIDFLFDGI
MQFTVYANTGKSAVYPLLLDVTSDIIGQLNRRVVIPLLPIEKYPASTRPERLNPLVRLVDDNEYAVMTHEMASIPVRILG
AEFCDASQYRTKVKAAIDFLFDGI
Download Length: 315 bp
>T55761 NZ_CP012096:c639672-639358 [Serratia plymuthica]
ATGCAATTTACGGTATACGCGAATACAGGGAAAAGCGCAGTCTATCCTCTGCTGCTTGATGTGACGAGCGATATCATTGG
GCAATTAAATCGCCGAGTTGTGATCCCGTTATTACCCATTGAAAAGTATCCGGCCAGTACTCGCCCGGAACGCTTGAACC
CTTTGGTCAGGCTGGTGGATGACAACGAGTACGCCGTTATGACCCATGAGATGGCAAGTATTCCCGTTCGTATCCTGGGC
GCTGAATTTTGCGATGCTTCCCAATACCGAACCAAGGTGAAAGCCGCAATAGATTTTCTTTTCGACGGTATCTGA
ATGCAATTTACGGTATACGCGAATACAGGGAAAAGCGCAGTCTATCCTCTGCTGCTTGATGTGACGAGCGATATCATTGG
GCAATTAAATCGCCGAGTTGTGATCCCGTTATTACCCATTGAAAAGTATCCGGCCAGTACTCGCCCGGAACGCTTGAACC
CTTTGGTCAGGCTGGTGGATGACAACGAGTACGCCGTTATGACCCATGAGATGGCAAGTATTCCCGTTCGTATCCTGGGC
GCTGAATTTTGCGATGCTTCCCAATACCGAACCAAGGTGAAAGCCGCAATAGATTTTCTTTTCGACGGTATCTGA
Antitoxin
Download Length: 79 a.a. Molecular weight: 9078.16 Da Isoelectric Point: 6.7184
>AT55761 WP_020438746.1 NZ_CP012096:c639911-639675 [Serratia plymuthica]
MPVKQRTTQSVTMAVERSLLSRAREAGINLSATLNAALDAELRQHEMRKWKEENREAIDALNRFHDEHGCFSDEYRTF
MPVKQRTTQSVTMAVERSLLSRAREAGINLSATLNAALDAELRQHEMRKWKEENREAIDALNRFHDEHGCFSDEYRTF
Download Length: 237 bp
>AT55761 NZ_CP012096:c639911-639675 [Serratia plymuthica]
ATGCCAGTAAAACAACGAACGACCCAAAGCGTTACCATGGCGGTGGAACGCAGTTTACTGAGCCGTGCACGTGAGGCGGG
CATTAACCTCAGTGCTACGCTGAATGCTGCTTTGGATGCAGAATTGCGTCAGCATGAGATGAGAAAATGGAAGGAAGAAA
ACCGAGAAGCGATCGATGCTTTAAATCGTTTTCATGATGAACATGGCTGTTTCAGTGACGAATACAGGACGTTTTAG
ATGCCAGTAAAACAACGAACGACCCAAAGCGTTACCATGGCGGTGGAACGCAGTTTACTGAGCCGTGCACGTGAGGCGGG
CATTAACCTCAGTGCTACGCTGAATGCTGCTTTGGATGCAGAATTGCGTCAGCATGAGATGAGAAAATGGAAGGAAGAAA
ACCGAGAAGCGATCGATGCTTTAAATCGTTTTCATGATGAACATGGCTGTTTCAGTGACGAATACAGGACGTTTTAG