Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1522289..1522839 Replicon chromosome
Accession NZ_CP012071
Organism Selenomonas sp. oral taxon 478 strain F0592

Toxin (Protein)


Gene name relE Uniprot ID A0A0K1FHU1
Locus tag ADJ74_RS07110 Protein ID WP_050343058.1
Coordinates 1522289..1522570 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E0NYP4
Locus tag ADJ74_RS07115 Protein ID WP_009442906.1
Coordinates 1522567..1522839 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ADJ74_RS07095 1517310..1519214 + 1905 WP_050343052.1 NADH-quinone oxidoreductase subunit L -
ADJ74_RS07100 1519211..1520740 + 1530 WP_050343054.1 NADH-quinone oxidoreductase subunit M -
ADJ74_RS07105 1520740..1522194 + 1455 WP_050343056.1 NADH-quinone oxidoreductase subunit N -
ADJ74_RS07110 1522289..1522570 - 282 WP_050343058.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
ADJ74_RS07115 1522567..1522839 - 273 WP_009442906.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ADJ74_RS07125 1523347..1524063 - 717 WP_050343062.1 hypothetical protein -
ADJ74_RS07130 1524060..1525676 - 1617 WP_050343065.1 ATP-binding cassette domain-containing protein -
ADJ74_RS07135 1525673..1527316 - 1644 WP_050343067.1 thiol reductant ABC exporter subunit CydD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10869.42 Da        Isoelectric Point: 7.4705

>T55604 WP_050343058.1 NZ_CP012071:c1522570-1522289 [Selenomonas sp. oral taxon 478]
MTYHIKFTNAYKKSYKRAKKRGLNLKLLDNVVEALGQGHKLDAKYRDHALHGNWEGFRECHIQPDWLLIYLVENDVLTLT
LVETGTHADIFDE

Download         Length: 282 bp

>T55604 NZ_CP012071:c1522570-1522289 [Selenomonas sp. oral taxon 478]
ATGACCTATCACATCAAGTTCACCAACGCTTATAAGAAAAGTTACAAGCGTGCCAAGAAACGCGGCTTGAATCTCAAGCT
ACTGGATAATGTTGTTGAAGCATTGGGACAGGGGCACAAGCTAGATGCCAAATACCGTGACCATGCACTTCATGGCAATT
GGGAGGGATTTCGCGAGTGCCATATTCAACCGGATTGGTTGTTGATATACCTCGTTGAAAACGACGTCCTAACCTTGACC
CTAGTCGAAACTGGAACCCATGCAGACATATTCGATGAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10055.54 Da        Isoelectric Point: 5.6630

>AT55604 WP_009442906.1 NZ_CP012071:c1522839-1522567 [Selenomonas sp. oral taxon 478]
MSTVPTQIRIDRNIKEQASALFSGLGLDMSGAVNMFLHQCVLRGGIPFSIEMPHYKQSTLAAMEEARKISRNPDVPSYDN
MDDLKKALEE

Download         Length: 273 bp

>AT55604 NZ_CP012071:c1522839-1522567 [Selenomonas sp. oral taxon 478]
ATGTCAACCGTCCCTACTCAAATAAGAATTGACCGGAACATAAAAGAACAGGCTAGCGCATTGTTCTCTGGGCTGGGCCT
AGATATGTCCGGTGCCGTTAATATGTTTCTCCATCAGTGTGTCCTTCGTGGAGGCATCCCATTTTCTATCGAAATGCCCC
ATTATAAACAAAGCACCTTGGCGGCTATGGAAGAAGCAAGAAAAATCTCCCGCAACCCGGATGTTCCTAGCTATGACAAC
ATGGACGACTTGAAGAAGGCATTGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K1FHU1

Antitoxin

Source ID Structure
AlphaFold DB A0A0K1FIK1

References