Detailed information of TA system TA055587

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 31768..32399
• Replicon: plasmid pNX47
• Accession: NZ_CP012062
• Organism: Xanthomonas sp. ISO98C4

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: AC801_RS24590
• Protein ID: WP_127446657.1
• Coordinates: 31768..32148 (-)
• Length: 127 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: U4M4Z6
• Locus tag: AC801_RS24595
• Protein ID: WP_022557731.1
• Coordinates: 32145..32399 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AC801_RS24580	28554..30101	+	1548	WP_080720984.1	HAD hydrolase-like protein	-
AC801_RS24585	30685..31771	+	1087	Protein_32	IS3 family transposase	-
AC801_RS24590	31768..32148	-	381	WP_127446657.1	type II toxin-antitoxin system VapC family toxin	Toxin
AC801_RS24595	32145..32399	-	255	WP_022557731.1	plasmid stability protein	Antitoxin
AC801_RS24600	32611..33204	+	594	WP_022560487.1	recombinase family protein	-
AC801_RS24605	33201..36230	+	3030	WP_022560486.1	Tn3 family transposase	-
AC801_RS24610	36262..36638	-	377	Protein_37	transposase	-
AC801_RS24620	36890..37210	+	321	WP_033481941.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..46595	46595
	-	inside	IScluster/Tn	-	-	20822..42107	21285

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-114)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 127 a.a.
• Molecular weight: 13673.74 Da
• Isoelectric Point: 7.0125

>T55587 WP_127446657.1 NZ_CP012062:c32148-31768 [Xanthomonas sp. ISO98C4]
MIVLDTNVVSEAMKPEPHPSVRTWLNDQAAETLYLSSVTLAELLFGIAALPAGKRKDMLEQALDGLMGLFRDRVLPFDID
AARRYAELAVTAKIGGRGFPTPDGYIAAIAASRGNPPTFSGRQKWS

Nucleotide

• Length: 381 bp

>T55587 NZ_CP012062:c32148-31768 [Xanthomonas sp. ISO98C4]
ATGATCGTTCTCGATACCAACGTCGTTTCCGAGGCGATGAAGCCCGAGCCGCACCCATCCGTGCGGACCTGGTTGAACGA
TCAAGCCGCTGAAACACTGTACCTGTCCAGCGTGACGCTGGCCGAACTGCTATTTGGCATCGCTGCGCTTCCTGCCGGTA
AGCGCAAGGACATGCTGGAACAGGCCCTTGATGGCCTCATGGGCCTGTTTAGGGATCGGGTGTTGCCATTCGACATCGAT
GCAGCGCGGCGTTATGCCGAATTGGCCGTGACGGCAAAGATCGGAGGGCGAGGATTTCCGACACCCGACGGCTACATCGC
AGCGATTGCTGCCTCGCGGGGTAATCCCCCCACTTTTAGCGGTCGCCAGAAGTGGAGCTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9388.80 Da
• Isoelectric Point: 8.9326

>AT55587 WP_022557731.1 NZ_CP012062:c32399-32145 [Xanthomonas sp. ISO98C4]
MAMLTVRNLPDDVHRALRMRAAQNGHSTEAEVREILATAVKPETRVRLGEALAALGRKIGLTNEDFEVFDRVRDKTPAVP
PRLE

Nucleotide

• Length: 255 bp

>AT55587 NZ_CP012062:c32399-32145 [Xanthomonas sp. ISO98C4]
ATGGCAATGCTGACAGTACGTAATCTGCCGGATGATGTGCACCGCGCATTGCGCATGCGGGCCGCTCAAAATGGGCACAG
CACCGAGGCCGAGGTCCGCGAGATTCTGGCGACCGCAGTCAAGCCAGAGACGCGCGTTCGCCTAGGCGAAGCCTTGGCGG
CTTTGGGTCGCAAGATTGGCCTGACGAATGAGGACTTCGAGGTCTTCGATCGGGTAAGAGACAAGACGCCGGCCGTCCCG
CCGAGGCTTGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A3T0G545