Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 31768..32399 Replicon plasmid pNX47
Accession NZ_CP012062
Organism Xanthomonas sp. ISO98C4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag AC801_RS24590 Protein ID WP_127446657.1
Coordinates 31768..32148 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID U4M4Z6
Locus tag AC801_RS24595 Protein ID WP_022557731.1
Coordinates 32145..32399 (-) Length 85 a.a.

Genomic Context

AC801_RS24580AC801_RS24585AC801_RS24600AC801_RS24605AC801_RS24620AC801_RS24590AC801_RS24595AC801_RS24610
Location: 28554..30101 (1548 bp)
Type: Others
Protein ID: WP_080720984.1
Location: 30685..31771 (1087 bp)
Type: Others
Protein ID: Protein_32
Location: 32611..33204 (594 bp)
Type: Others
Protein ID: WP_022560487.1
Location: 33201..36230 (3030 bp)
Type: Others
Protein ID: WP_022560486.1
Location: 36890..37210 (321 bp)
Type: Others
Protein ID: WP_033481941.1
Location: 31768..32148 (381 bp)
Type: Toxin
Protein ID: WP_127446657.1
Location: 32145..32399 (255 bp)
Type: Antitoxin
Protein ID: WP_022557731.1
Location: 36262..36638 (377 bp)
Type: Others
Protein ID: Protein_37
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AC801_RS2458028554..30101+1548WP_080720984.1HAD hydrolase-like protein-
AC801_RS2458530685..31771+1087Protein_32IS3 family transposase-
AC801_RS2459031768..32148-381WP_127446657.1type II toxin-antitoxin system VapC family toxinToxin
AC801_RS2459532145..32399-255WP_022557731.1plasmid stability proteinAntitoxin
AC801_RS2460032611..33204+594WP_022560487.1recombinase family protein-
AC801_RS2460533201..36230+3030WP_022560486.1Tn3 family transposase-
AC801_RS2461036262..36638-377Protein_37transposase-
AC801_RS2462036890..37210+321WP_033481941.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..4659546595
-insideIScluster/Tn--20822..4210721285


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-114)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13673.74 Da        Isoelectric Point: 7.0125

>T55587 WP_127446657.1 NZ_CP012062:c32148-31768 [Xanthomonas sp. ISO98C4]
MIVLDTNVVSEAMKPEPHPSVRTWLNDQAAETLYLSSVTLAELLFGIAALPAGKRKDMLEQALDGLMGLFRDRVLPFDID
AARRYAELAVTAKIGGRGFPTPDGYIAAIAASRGNPPTFSGRQKWS

Download         Length: 381 bp

>T55587 NZ_CP012062:c32148-31768 [Xanthomonas sp. ISO98C4]
ATGATCGTTCTCGATACCAACGTCGTTTCCGAGGCGATGAAGCCCGAGCCGCACCCATCCGTGCGGACCTGGTTGAACGA
TCAAGCCGCTGAAACACTGTACCTGTCCAGCGTGACGCTGGCCGAACTGCTATTTGGCATCGCTGCGCTTCCTGCCGGTA
AGCGCAAGGACATGCTGGAACAGGCCCTTGATGGCCTCATGGGCCTGTTTAGGGATCGGGTGTTGCCATTCGACATCGAT
GCAGCGCGGCGTTATGCCGAATTGGCCGTGACGGCAAAGATCGGAGGGCGAGGATTTCCGACACCCGACGGCTACATCGC
AGCGATTGCTGCCTCGCGGGGTAATCCCCCCACTTTTAGCGGTCGCCAGAAGTGGAGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9388.80 Da        Isoelectric Point: 8.9326

>AT55587 WP_022557731.1 NZ_CP012062:c32399-32145 [Xanthomonas sp. ISO98C4]
MAMLTVRNLPDDVHRALRMRAAQNGHSTEAEVREILATAVKPETRVRLGEALAALGRKIGLTNEDFEVFDRVRDKTPAVP
PRLE

Download         Length: 255 bp

>AT55587 NZ_CP012062:c32399-32145 [Xanthomonas sp. ISO98C4]
ATGGCAATGCTGACAGTACGTAATCTGCCGGATGATGTGCACCGCGCATTGCGCATGCGGGCCGCTCAAAATGGGCACAG
CACCGAGGCCGAGGTCCGCGAGATTCTGGCGACCGCAGTCAAGCCAGAGACGCGCGTTCGCCTAGGCGAAGCCTTGGCGG
CTTTGGGTCGCAAGATTGGCCTGACGAATGAGGACTTCGAGGTCTTCGATCGGGTAAGAGACAAGACGCCGGCCGTCCCG
CCGAGGCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3T0G545

References