Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4627746..4628107 Replicon chromosome
Accession NZ_CP012060
Organism Xanthomonas sp. ISO98C4

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AC801_RS21295 Protein ID WP_005914328.1
Coordinates 4627746..4627880 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag AC801_RS21300 Protein ID WP_039568455.1
Coordinates 4627955..4628107 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC801_RS21275 4624439..4624694 + 256 Protein_3949 hypothetical protein -
AC801_RS21280 4624762..4625796 - 1035 WP_046736011.1 MBL fold metallo-hydrolase -
AC801_RS21285 4625836..4627125 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
AC801_RS21290 4627307..4627516 - 210 WP_003486601.1 CsbD family protein -
AC801_RS21295 4627746..4627880 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AC801_RS21300 4627955..4628107 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
AC801_RS21305 4628214..4629137 - 924 WP_039568453.1 arginase -
AC801_RS21310 4629458..4629910 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
AC801_RS21315 4629974..4630333 + 360 WP_003486613.1 hypothetical protein -
AC801_RS21320 4630430..4631347 + 918 WP_039568451.1 hypothetical protein -
AC801_RS21325 4631344..4631886 + 543 WP_039568446.1 GTPase -
AC801_RS21335 4632355..4633038 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T55584 WP_005914328.1 NZ_CP012060:c4627880-4627746 [Xanthomonas sp. ISO98C4]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T55584 NZ_CP012060:c4627880-4627746 [Xanthomonas sp. ISO98C4]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT55584 WP_039568455.1 NZ_CP012060:c4628107-4627955 [Xanthomonas sp. ISO98C4]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55584 NZ_CP012060:c4628107-4627955 [Xanthomonas sp. ISO98C4]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References