55580

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4621688..4622049 Replicon chromosome
Accession NZ_CP012057
Organism Xanthomonas phaseoli pv. phaseoli strain ISO98C12

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AC611_RS21235 Protein ID WP_005914328.1
Coordinates 4621688..4621822 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag AC611_RS21240 Protein ID WP_039568455.1
Coordinates 4621897..4622049 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC611_RS21215 4618381..4618636 + 256 Protein_3939 hypothetical protein -
AC611_RS21220 4618704..4619738 - 1035 WP_046736011.1 MBL fold metallo-hydrolase -
AC611_RS21225 4619778..4621067 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
AC611_RS21230 4621249..4621458 - 210 WP_003486601.1 CsbD family protein -
AC611_RS21235 4621688..4621822 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AC611_RS21240 4621897..4622049 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
AC611_RS21245 4622156..4623079 - 924 WP_039568453.1 arginase -
AC611_RS21250 4623400..4623852 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
AC611_RS21255 4623916..4624275 + 360 WP_003486613.1 hypothetical protein -
AC611_RS21260 4624372..4625289 + 918 WP_039568451.1 hypothetical protein -
AC611_RS21265 4625286..4625828 + 543 WP_039568446.1 GTPase -
AC611_RS21275 4626297..4626980 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T55580 WP_005914328.1 NZ_CP012057:c4621822-4621688 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T55580 NZ_CP012057:c4621822-4621688 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT55580 WP_039568455.1 NZ_CP012057:c4622049-4621897 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55580 NZ_CP012057:c4622049-4621897 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References