Detailed information of TA system TA055579

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 5259053..5259590
• Replicon: chromosome
• Accession: NZ_CP012055
• Organism: Xanthomonas citri pv. fuscans strain ISO12C3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9YU06
• Locus tag: AC612_RS23685
• Protein ID: WP_017158383.1
• Coordinates: 5259309..5259590 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7X9UWY6
• Locus tag: AC612_RS23680
• Protein ID: WP_017158384.1
• Coordinates: 5259053..5259322 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AC612_RS23650	5254318..5254926	+	609	WP_017154888.1	hypothetical protein	-
AC612_RS23655	5255039..5255671	+	633	WP_007966093.1	ParA family protein	-
AC612_RS23660	5255664..5255996	+	333	WP_007966095.1	hypothetical protein	-
AC612_RS23665	5256063..5256347	+	285	WP_017154887.1	hypothetical protein	-
AC612_RS23670	5256354..5257541	+	1188	WP_046735718.1	zeta toxin family protein	-
AC612_RS23675	5257982..5258944	+	963	WP_011345584.1	recombinase family protein	-
AC612_RS23680	5259053..5259322	+	270	WP_017158384.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AC612_RS23685	5259309..5259590	+	282	WP_017158383.1	type II toxin-antitoxin system YafQ family toxin	Toxin
AC612_RS23690	5259728..5260125	-	398	Protein_4445	hypothetical protein	-
AC612_RS23695	5260171..5260878	-	708	WP_046935361.1	hypothetical protein	-
AC612_RS23700	5260875..5261321	-	447	WP_127472339.1	conjugal transfer protein TraD	-
AC612_RS23705	5261669..5262064	+	396	WP_011345590.1	hypothetical protein	-
AC612_RS23710	5262162..5262431	+	270	WP_017171908.1	hypothetical protein	-
AC612_RS23715	5262428..5262721	+	294	WP_011345592.1	type II toxin-antitoxin system RelE/ParE family toxin	-
AC612_RS23720	5262834..5263454	+	621	WP_011345593.1	hypothetical protein	-
AC612_RS24885	5263653..5263994	+	342	WP_029561219.1	hypothetical protein	-
AC612_RS23730	5264066..5264263	+	198	WP_019303588.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-86)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10679.06 Da
• Isoelectric Point: 8.9188

>T55579 WP_017158383.1 NZ_CP012055:5259309-5259590 [Xanthomonas citri pv. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Nucleotide

• Length: 282 bp

>T55579 NZ_CP012055:5259309-5259590 [Xanthomonas citri pv. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9719.10 Da
• Isoelectric Point: 5.6976

>AT55579 WP_017158384.1 NZ_CP012055:5259053-5259322 [Xanthomonas citri pv. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Nucleotide

• Length: 270 bp

>AT55579 NZ_CP012055:5259053-5259322 [Xanthomonas citri pv. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Structures

Toxin

• AlphaFold DB: A0A7X9YU06

Antitoxin

• AlphaFold DB: A0A7X9UWY6