55578

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4800155..4800516 Replicon chromosome
Accession NZ_CP012055
Organism Xanthomonas citri pv. fuscans strain ISO12C3

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AC612_RS21720 Protein ID WP_005914328.1
Coordinates 4800155..4800289 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AC612_RS21725 Protein ID WP_003486606.1
Coordinates 4800364..4800516 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC612_RS21700 4795847..4796890 - 1044 WP_033481136.1 MBL fold metallo-hydrolase -
AC612_RS21705 4796920..4798209 - 1290 WP_022560228.1 tryptophan--tRNA ligase -
AC612_RS21710 4798426..4799652 + 1227 WP_099868307.1 IS256-like element ISXax1 family transposase -
AC612_RS21715 4799719..4799928 - 210 WP_016904514.1 CsbD family protein -
AC612_RS21720 4800155..4800289 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AC612_RS21725 4800364..4800516 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AC612_RS21730 4800623..4801546 - 924 WP_046735866.1 arginase -
AC612_RS21735 4801867..4802319 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
AC612_RS21740 4802383..4802742 + 360 WP_003486613.1 hypothetical protein -
AC612_RS21745 4802839..4803753 + 915 WP_022560229.1 hypothetical protein -
AC612_RS21750 4803750..4804292 + 543 WP_003486615.1 GTPase -
AC612_RS21755 4804772..4805455 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 4798426..4799652 1226


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T55578 WP_005914328.1 NZ_CP012055:c4800289-4800155 [Xanthomonas citri pv. fuscans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T55578 NZ_CP012055:c4800289-4800155 [Xanthomonas citri pv. fuscans]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT55578 WP_003486606.1 NZ_CP012055:c4800516-4800364 [Xanthomonas citri pv. fuscans]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55578 NZ_CP012055:c4800516-4800364 [Xanthomonas citri pv. fuscans]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References