Detailed information of TA system TA055576

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 5258186..5258723
• Replicon: chromosome
• Accession: NZ_CP012053
• Organism: Xanthomonas citri pv. fuscans strain ISO118C1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9YU06
• Locus tag: AC613_RS23695
• Protein ID: WP_017158383.1
• Coordinates: 5258442..5258723 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7X9UWY6
• Locus tag: AC613_RS23690
• Protein ID: WP_017158384.1
• Coordinates: 5258186..5258455 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AC613_RS23660	5253448..5254056	+	609	WP_017154888.1	hypothetical protein	-
AC613_RS23665	5254169..5254801	+	633	WP_007966093.1	ParA family protein	-
AC613_RS23670	5254794..5255126	+	333	WP_007966095.1	hypothetical protein	-
AC613_RS23675	5255193..5255477	+	285	WP_017154887.1	hypothetical protein	-
AC613_RS23680	5255484..5256671	+	1188	WP_046735718.1	zeta toxin family protein	-
AC613_RS23685	5257115..5258077	+	963	WP_022560476.1	recombinase family protein	-
AC613_RS23690	5258186..5258455	+	270	WP_017158384.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AC613_RS23695	5258442..5258723	+	282	WP_017158383.1	type II toxin-antitoxin system YafQ family toxin	Toxin
AC613_RS23700	5258861..5259258	-	398	Protein_4445	hypothetical protein	-
AC613_RS23705	5259304..5260011	-	708	WP_022560478.1	hypothetical protein	-
AC613_RS23710	5260008..5260454	-	447	WP_033481413.1	hypothetical protein	-
AC613_RS23715	5260800..5261195	+	396	WP_022560480.1	hypothetical protein	-
AC613_RS23720	5261293..5261562	+	270	WP_033481412.1	hypothetical protein	-
AC613_RS23725	5261559..5261852	+	294	WP_046735719.1	type II toxin-antitoxin system RelE/ParE family toxin	-
AC613_RS23730	5261965..5262585	+	621	WP_011345593.1	hypothetical protein	-
AC613_RS24920	5262784..5263125	+	342	WP_029561219.1	hypothetical protein	-
AC613_RS23740	5263197..5263394	+	198	WP_022560481.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-86)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10679.06 Da
• Isoelectric Point: 8.9188

>T55576 WP_017158383.1 NZ_CP012053:5258442-5258723 [Xanthomonas citri pv. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Nucleotide

• Length: 282 bp

>T55576 NZ_CP012053:5258442-5258723 [Xanthomonas citri pv. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9719.10 Da
• Isoelectric Point: 5.6976

>AT55576 WP_017158384.1 NZ_CP012053:5258186-5258455 [Xanthomonas citri pv. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Nucleotide

• Length: 270 bp

>AT55576 NZ_CP012053:5258186-5258455 [Xanthomonas citri pv. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Structures

Toxin

• AlphaFold DB: A0A7X9YU06

Antitoxin

• AlphaFold DB: A0A7X9UWY6