Detailed information of TA system TA055573

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 5258188..5258725
• Replicon: chromosome
• Accession: NZ_CP012051
• Organism: Xanthomonas citri pv. fuscans strain ISO118C5

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A7X9YU06
• Locus tag: AC614_RS23690
• Protein ID: WP_017158383.1
• Coordinates: 5258444..5258725 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7X9UWY6
• Locus tag: AC614_RS23685
• Protein ID: WP_017158384.1
• Coordinates: 5258188..5258457 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AC614_RS23655	5253450..5254058	+	609	WP_017154888.1	hypothetical protein	-
AC614_RS23660	5254171..5254803	+	633	WP_007966093.1	ParA family protein	-
AC614_RS23665	5254796..5255128	+	333	WP_007966095.1	hypothetical protein	-
AC614_RS23670	5255195..5255479	+	285	WP_017154887.1	hypothetical protein	-
AC614_RS23675	5255486..5256673	+	1188	WP_046735718.1	zeta toxin family protein	-
AC614_RS23680	5257117..5258079	+	963	WP_022560476.1	recombinase family protein	-
AC614_RS23685	5258188..5258457	+	270	WP_017158384.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AC614_RS23690	5258444..5258725	+	282	WP_017158383.1	type II toxin-antitoxin system YafQ family toxin	Toxin
AC614_RS23695	5258863..5259260	-	398	Protein_4444	hypothetical protein	-
AC614_RS23700	5259306..5260013	-	708	WP_022560478.1	hypothetical protein	-
AC614_RS23705	5260010..5260456	-	447	WP_033481413.1	hypothetical protein	-
AC614_RS23710	5260802..5261197	+	396	WP_022560480.1	hypothetical protein	-
AC614_RS23715	5261295..5261564	+	270	WP_033481412.1	hypothetical protein	-
AC614_RS23720	5261561..5261854	+	294	WP_046735719.1	type II toxin-antitoxin system RelE/ParE family toxin	-
AC614_RS23725	5261967..5262587	+	621	WP_011345593.1	hypothetical protein	-
AC614_RS24905	5262786..5263127	+	342	WP_029561219.1	hypothetical protein	-
AC614_RS23735	5263199..5263396	+	198	WP_022560481.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-86)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10679.06 Da
• Isoelectric Point: 8.9188

>T55573 WP_017158383.1 NZ_CP012051:5258444-5258725 [Xanthomonas citri pv. fuscans]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Nucleotide

• Length: 282 bp

>T55573 NZ_CP012051:5258444-5258725 [Xanthomonas citri pv. fuscans]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCTGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCTCGCACAGCGAGCTTTTCGGCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9719.10 Da
• Isoelectric Point: 5.6976

>AT55573 WP_017158384.1 NZ_CP012051:5258188-5258457 [Xanthomonas citri pv. fuscans]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Nucleotide

• Length: 270 bp

>AT55573 NZ_CP012051:5258188-5258457 [Xanthomonas citri pv. fuscans]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Structures

Toxin

• AlphaFold DB: A0A7X9YU06

Antitoxin

• AlphaFold DB: A0A7X9UWY6