Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 65989..66533 Replicon chromosome
Accession NZ_CP012051
Organism Xanthomonas citri pv. fuscans strain ISO118C5

Toxin (Protein)


Gene name relE Uniprot ID A0A808FED4
Locus tag AC614_RS00300 Protein ID WP_022557812.1
Coordinates 66234..66533 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag AC614_RS00295 Protein ID WP_005912560.1
Coordinates 65989..66246 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC614_RS00280 61092..62591 - 1500 WP_046735535.1 ribonuclease H-like domain-containing protein -
AC614_RS00285 62588..65083 - 2496 WP_164745078.1 DEAD/DEAH box helicase -
AC614_RS00290 65261..65923 + 663 WP_029818121.1 hemolysin III family protein -
AC614_RS00295 65989..66246 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AC614_RS00300 66234..66533 + 300 WP_022557812.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AC614_RS00310 66713..67612 - 900 WP_022557813.1 SDR family NAD(P)-dependent oxidoreductase -
AC614_RS00315 67672..68409 - 738 WP_022557814.1 SDR family oxidoreductase -
AC614_RS00320 68535..69446 + 912 WP_039732218.1 LysR family transcriptional regulator -
AC614_RS00325 69661..70725 - 1065 WP_033481295.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11279.07 Da        Isoelectric Point: 10.1539

>T55571 WP_022557812.1 NZ_CP012051:66234-66533 [Xanthomonas citri pv. fuscans]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIERPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T55571 NZ_CP012051:66234-66533 [Xanthomonas citri pv. fuscans]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACGCCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT55571 WP_005912560.1 NZ_CP012051:65989-66246 [Xanthomonas citri pv. fuscans]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT55571 NZ_CP012051:65989-66246 [Xanthomonas citri pv. fuscans]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808FED4

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References