55567

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4622001..4622362 Replicon chromosome
Accession NZ_CP012048
Organism Xanthomonas phaseoli pv. phaseoli strain ISO18C2

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AC609_RS21240 Protein ID WP_005914328.1
Coordinates 4622001..4622135 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A3Q9Q401
Locus tag AC609_RS21245 Protein ID WP_039568455.1
Coordinates 4622210..4622362 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC609_RS21220 4618694..4618949 + 256 Protein_3933 hypothetical protein -
AC609_RS21225 4619017..4620051 - 1035 WP_046736011.1 MBL fold metallo-hydrolase -
AC609_RS21230 4620091..4621380 - 1290 WP_039568540.1 tryptophan--tRNA ligase -
AC609_RS21235 4621562..4621771 - 210 WP_003486601.1 CsbD family protein -
AC609_RS21240 4622001..4622135 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AC609_RS21245 4622210..4622362 - 153 WP_039568455.1 entericidin A/B family lipoprotein Antitoxin
AC609_RS21250 4622469..4623392 - 924 WP_039568453.1 arginase -
AC609_RS21255 4623713..4624165 + 453 WP_017158238.1 roadblock/LC7 domain-containing protein -
AC609_RS21260 4624229..4624588 + 360 WP_003486613.1 hypothetical protein -
AC609_RS21265 4624685..4625602 + 918 WP_039568451.1 hypothetical protein -
AC609_RS21270 4625599..4626141 + 543 WP_039568446.1 GTPase -
AC609_RS21280 4626610..4627293 + 684 WP_039568445.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T55567 WP_005914328.1 NZ_CP012048:c4622135-4622001 [Xanthomonas phaseoli pv. phaseoli]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T55567 NZ_CP012048:c4622135-4622001 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5138.07 Da        Isoelectric Point: 8.7942

>AT55567 WP_039568455.1 NZ_CP012048:c4622362-4622210 [Xanthomonas phaseoli pv. phaseoli]
MKRLLTLMVLGLFSSGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55567 NZ_CP012048:c4622362-4622210 [Xanthomonas phaseoli pv. phaseoli]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGTCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q9Q401

References