Detailed information of TA system TA055550

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): TfiT-relB/YafQ-DinJ
• Location: 1629715..1630258
• Replicon: chromosome
• Accession: NZ_CP012033
• Organism: Levilactobacillus koreensis strain 26-25

Toxin (Protein)

• Gene name: TfiT
• Uniprot ID: -
• Locus tag: ABN16_RS13750
• Protein ID: WP_082153344.1
• Coordinates: 1630094..1630258 (+)
• Length: 55 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ABN16_RS07280
• Protein ID: WP_048734391.1
• Coordinates: 1629715..1629987 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABN16_RS07270	1626092..1627786	+	1695	WP_048734386.1	oleate hydratase	-
ABN16_RS07275	1628053..1629639	+	1587	WP_048734389.1	ABC transporter ATP-binding protein/permease	-
ABN16_RS07280	1629715..1629987	+	273	WP_048734391.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
ABN16_RS13750	1630094..1630258	+	165	WP_082153344.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
ABN16_RS07285	1630334..1630918	-	585	WP_048734394.1	signal peptidase I	-
ABN16_RS07290	1631146..1631538	+	393	WP_048734396.1	cytidine deaminase	-
ABN16_RS07300	1632456..1632809	+	354	WP_048734400.1	PadR family transcriptional regulator	-
ABN16_RS07305	1632812..1634314	+	1503	WP_048734403.1	DUF4097 family beta strand repeat protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (4-51)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-81)

Sequences

Toxin

Protein

• Length: 55 a.a.
• Molecular weight: 6409.50 Da
• Isoelectric Point: 6.2051

>T55550 WP_082153344.1 NZ_CP012033:1630094-1630258 [Levilactobacillus koreensis]
MIRNYDYHILKGDKSGVSELHLERNWILIYEIVGKDELVLLLLDTGIHDILKFR

Nucleotide

• Length: 165 bp

>T55550 NZ_CP012033:1630094-1630258 [Levilactobacillus koreensis]
CTGATAAGAAATTATGACTATCACATTTTAAAAGGTGATAAATCAGGAGTTAGTGAACTTCATCTAGAGCGTAATTGGAT
TTTAATCTATGAAATAGTTGGAAAAGATGAGCTTGTTTTATTACTGTTGGATACCGGGATACATGATATTCTTAAATTTC
GTTAG

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10311.64 Da
• Isoelectric Point: 8.4695

>AT55550 WP_048734391.1 NZ_CP012033:1629715-1629987 [Levilactobacillus koreensis]
MQNVEKDRISIRVDRSRKEAAQKVFNEMGLDLGTAINIFLAQSIRDQALPFRPSVYGQRLTQALKEAKNGDVTTFDNEKA
FYRYLDNLGD

Nucleotide

• Length: 273 bp

>AT55550 NZ_CP012033:1629715-1629987 [Levilactobacillus koreensis]
ATGCAAAATGTGGAAAAAGATAGGATCAGCATCCGCGTTGATCGTAGTCGAAAGGAAGCAGCACAGAAGGTTTTTAATGA
AATGGGATTAGATTTGGGAACAGCTATCAATATATTTTTAGCCCAGTCAATTCGTGACCAAGCCCTTCCATTTCGCCCTT
CTGTTTATGGCCAGCGTCTAACACAAGCGCTGAAAGAAGCAAAAAATGGTGATGTTACAACGTTTGATAATGAGAAGGCG
TTTTATCGATATTTAGATAATTTGGGGGACTAA