55549

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907(toxin)
Location 1006316..1006884 Replicon chromosome
Accession NZ_CP012033
Organism Levilactobacillus koreensis strain 26-25

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag ABN16_RS04555 Protein ID WP_048733272.1
Coordinates 1006316..1006666 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag ABN16_RS04560 Protein ID WP_048733274.1
Coordinates 1006666..1006884 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABN16_RS04530 1002393..1002842 + 450 WP_082153194.1 YhcH/YjgK/YiaL family protein -
ABN16_RS04535 1002856..1004106 + 1251 WP_048733266.1 MFS transporter -
ABN16_RS04540 1004127..1004594 + 468 WP_048733267.1 YhcH/YjgK/YiaL family protein -
ABN16_RS04545 1004817..1005095 - 279 WP_048733269.1 hypothetical protein -
ABN16_RS04550 1005135..1005779 - 645 WP_048733271.1 hypothetical protein -
ABN16_RS04555 1006316..1006666 - 351 WP_048733272.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
ABN16_RS04560 1006666..1006884 - 219 WP_048733274.1 hypothetical protein Antitoxin
ABN16_RS04565 1007130..1007861 - 732 WP_048733275.1 L-ribulose-5-phosphate 4-epimerase -
ABN16_RS04570 1008345..1009223 - 879 WP_048733277.1 L-ribulose-5-phosphate 3-epimerase -
ABN16_RS04575 1009220..1010752 - 1533 WP_048733279.1 carbohydrate kinase -
ABN16_RS04580 1010772..1011773 - 1002 WP_082153195.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-106)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13543.31 Da        Isoelectric Point: 5.8187

>T55549 WP_048733272.1 NZ_CP012033:c1006666-1006316 [Levilactobacillus koreensis]
MTYMPKQKDIIWINFDPQRGREIKKRRPALVLSSDLYNRSTGFVIVAPITSTIRDLPGYLTLGDDYQIHGQVVAAQVYSF
DASTNANRQVDYIETMRDEDFYRAAQIVYYNFDFPF

Download         Length: 351 bp

>T55549 NZ_CP012033:c1006666-1006316 [Levilactobacillus koreensis]
ATGACATATATGCCTAAGCAAAAAGATATCATCTGGATTAATTTTGATCCGCAACGTGGCCGAGAGATTAAAAAACGCCG
CCCGGCTCTTGTACTCAGCAGTGACCTTTATAACCGGAGCACTGGCTTTGTGATTGTCGCTCCAATAACATCTACAATTA
GAGACTTACCTGGTTATCTGACTTTGGGTGATGATTACCAGATTCATGGTCAAGTTGTGGCCGCACAAGTCTATTCGTTT
GATGCATCGACCAACGCTAATCGTCAAGTCGATTACATTGAAACCATGCGTGATGAGGATTTCTATCGGGCTGCGCAGAT
TGTGTACTATAACTTTGATTTTCCGTTTTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8263.38 Da        Isoelectric Point: 5.0807

>AT55549 WP_048733274.1 NZ_CP012033:c1006884-1006666 [Levilactobacillus koreensis]
MMEVKTVSRGNSLALSLPKDDRFKKGQRWLLIPATDGESFTLVPKMENPYASKRDSKAMTEEWSDVNWSEVE

Download         Length: 219 bp

>AT55549 NZ_CP012033:c1006884-1006666 [Levilactobacillus koreensis]
ATGATGGAAGTAAAAACAGTAAGTCGCGGTAACTCTTTAGCACTGAGTTTGCCAAAGGATGATCGTTTTAAGAAGGGTCA
ACGCTGGCTACTAATTCCCGCTACGGACGGCGAATCCTTTACGTTAGTTCCTAAAATGGAAAATCCATATGCCTCTAAAA
GGGACTCAAAAGCCATGACTGAGGAATGGTCTGACGTTAATTGGAGCGAAGTAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References