Detailed information of TA system TA055540

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3091902..3092427
• Replicon: chromosome
• Accession: NZ_CP012023
• Organism: Celeribacter marinus strain IMCC12053

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A0N7HJ57
• Locus tag: IMCC12053_RS15430
• Protein ID: WP_062220622.1
• Coordinates: 3091902..3092192 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IMCC12053_RS15435
• Protein ID: WP_062218572.1
• Coordinates: 3092182..3092427 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMCC12053_RS15405	3087479..3088078	+	600	WP_062220608.1	hypothetical protein	-
IMCC12053_RS15410	3088075..3088635	+	561	WP_062220611.1	hypothetical protein	-
IMCC12053_RS15415	3088635..3089072	+	438	WP_062220614.1	hypothetical protein	-
IMCC12053_RS15420	3089076..3091675	+	2600	Protein_3030	host specificity protein J	-
IMCC12053_RS15425	3091675..3091905	+	231	WP_062220617.1	hypothetical protein	-
IMCC12053_RS15430	3091902..3092192	-	291	WP_062220622.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IMCC12053_RS15435	3092182..3092427	-	246	WP_062218572.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
IMCC12053_RS15440	3092525..3092836	+	312	WP_062220625.1	phage holin family protein	-
IMCC12053_RS15445	3092928..3093860	+	933	WP_062218568.1	TIGR02594 family protein	-
IMCC12053_RS15450	3093857..3094114	+	258	WP_062218566.1	hypothetical protein	-
IMCC12053_RS15455	3094250..3094603	+	354	WP_062220628.1	hypothetical protein	-
IMCC12053_RS15460	3094612..3094806	+	195	WP_143090059.1	hypothetical protein	-
IMCC12053_RS15465	3094806..3095921	+	1116	WP_062220632.1	head decoration protein	-
IMCC12053_RS15470	3095968..3096258	+	291	WP_062220635.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10997.82 Da
• Isoelectric Point: 10.7031

>T55540 WP_062220622.1 NZ_CP012023:c3092192-3091902 [Celeribacter marinus]
MSYDLQFLPSALKEWHKLGATLQSQFKKKLKERLAQPHVVADGLHGMPNHYKIKLRSAGYRLVYRIEDTTVTVTVVAVGK
RERGAVYKSAQKRFDP

Nucleotide

• Length: 291 bp

>T55540 NZ_CP012023:c3092192-3091902 [Celeribacter marinus]
ATGAGCTATGATCTGCAATTTTTGCCGTCAGCCCTAAAGGAATGGCATAAACTTGGTGCAACGCTGCAATCGCAATTTAA
AAAGAAGCTCAAAGAGCGGCTTGCACAGCCCCATGTTGTGGCCGACGGCCTTCACGGCATGCCAAACCACTACAAAATCA
AACTTCGCAGCGCGGGCTACCGCCTTGTCTACCGCATTGAAGATACCACTGTCACAGTAACGGTGGTGGCTGTGGGCAAG
CGCGAGCGTGGTGCTGTTTATAAAAGCGCGCAAAAACGCTTTGATCCTTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9008.35 Da
• Isoelectric Point: 4.7164

>AT55540 WP_062218572.1 NZ_CP012023:c3092427-3092182 [Celeribacter marinus]
MQRVEANVAVSVSDLKKNPSQVMAQAAGQSVAVLNHNRVMAYMVPAARYEAMMEHLDDLELADLIKQRVDETPVRVSLDE
L

Nucleotide

• Length: 246 bp

>AT55540 NZ_CP012023:c3092427-3092182 [Celeribacter marinus]
ATGCAGCGTGTCGAAGCCAATGTCGCCGTCAGCGTGTCCGATCTTAAAAAGAACCCCTCGCAGGTCATGGCGCAGGCGGC
AGGCCAATCTGTTGCCGTGCTGAACCACAACCGCGTCATGGCCTACATGGTGCCTGCCGCCCGCTACGAGGCCATGATGG
AGCATCTTGACGATTTGGAGCTGGCCGATCTGATCAAGCAGCGTGTGGACGAGACACCGGTGCGGGTCAGCTTGGATGAG
CTATGA

Structures

Toxin

• AlphaFold DB: A0A0N7HJ57