Detailed information of TA system TA055535

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1965398..1965923
• Replicon: chromosome
• Accession: NZ_CP012023
• Organism: Celeribacter marinus strain IMCC12053

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A0P0ACT6
• Locus tag: IMCC12053_RS09795
• Protein ID: WP_062218575.1
• Coordinates: 1965633..1965923 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IMCC12053_RS09790
• Protein ID: WP_062218572.1
• Coordinates: 1965398..1965643 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMCC12053_RS16005	1960786..1961556	-	771	WP_062218560.1	hypothetical protein	-
IMCC12053_RS09765	1961560..1961850	-	291	WP_062218562.1	hypothetical protein	-
IMCC12053_RS09770	1961897..1963012	-	1116	WP_062218564.1	head decoration protein	-
IMCC12053_RS09775	1963711..1963968	-	258	WP_062218566.1	hypothetical protein	-
IMCC12053_RS09780	1963965..1964897	-	933	WP_062218568.1	TIGR02594 family protein	-
IMCC12053_RS09785	1964989..1965300	-	312	WP_062218570.1	phage holin family protein	-
IMCC12053_RS09790	1965398..1965643	+	246	WP_062218572.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
IMCC12053_RS09795	1965633..1965923	+	291	WP_062218575.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IMCC12053_RS09800	1965920..1966150	-	231	WP_062218577.1	hypothetical protein	-
IMCC12053_RS09805	1966150..1968753	-	2604	WP_062218579.1	host specificity protein J	-
IMCC12053_RS09810	1968757..1969161	-	405	WP_062218581.1	hypothetical protein	-
IMCC12053_RS09815	1969236..1969538	+	303	WP_062218583.1	type II toxin-antitoxin system RelE/ParE family toxin	-
IMCC12053_RS09820	1969528..1969818	+	291	WP_062218585.1	putative addiction module antidote protein	-
IMCC12053_RS09825	1969832..1970392	-	561	WP_062218587.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1961897..2001601	39704

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10906.75 Da
• Isoelectric Point: 10.7031

>T55535 WP_062218575.1 NZ_CP012023:1965633-1965923 [Celeribacter marinus]
MSYDLQFLPSALKEWHKLGATLQSQFKKKLKERLAQPHVVADGLHGMPSHYKIKLRSAGYRLVYRIEDTTVTVTVVAVGK
RERGAVYKAAQKRVDP

Nucleotide

• Length: 291 bp

>T55535 NZ_CP012023:1965633-1965923 [Celeribacter marinus]
ATGAGCTATGATCTGCAATTTTTGCCGTCAGCCCTAAAGGAATGGCATAAACTCGGTGCAACGCTGCAATCGCAATTCAA
AAAGAAGCTCAAAGAGCGACTTGCGCAGCCCCATGTTGTGGCCGACGGCCTGCACGGCATGCCAAGCCACTACAAAATCA
AACTTCGCAGCGCAGGTTACCGCCTTGTCTACCGCATTGAAGATACCACTGTCACAGTAACGGTGGTGGCTGTGGGCAAG
CGCGAGCGTGGTGCTGTTTATAAGGCCGCGCAAAAACGCGTTGATCCTTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9008.35 Da
• Isoelectric Point: 4.7164

>AT55535 WP_062218572.1 NZ_CP012023:1965398-1965643 [Celeribacter marinus]
MQRVEANVAVSVSDLKKNPSQVMAQAAGQSVAVLNHNRVMAYMVPAARYEAMMEHLDDLELADLIKQRVDETPVRVSLDE
L

Nucleotide

• Length: 246 bp

>AT55535 NZ_CP012023:1965398-1965643 [Celeribacter marinus]
ATGCAGCGTGTTGAAGCCAATGTCGCCGTCAGCGTGTCCGATCTTAAAAAGAACCCCTCGCAGGTTATGGCGCAGGCGGC
AGGCCAATCTGTTGCCGTGCTGAACCACAACCGCGTCATGGCCTACATGGTGCCTGCCGCCCGCTACGAGGCCATGATGG
AGCATCTTGACGATTTGGAGCTGGCCGATCTGATCAAGCAGCGTGTGGACGAGACACCGGTGCGGGTCAGCTTGGATGAG
CTATGA

Structures

Toxin

• AlphaFold DB: A0A0P0ACT6