Detailed information of TA system TA055485

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): TsaAT/-
• Location: 912559..913035
• Replicon: chromosome
• Accession: NZ_CP012015
• Organism: Staphylococcus aureus strain Gv51

Toxin (Protein)

• Gene name: TsaT
• Uniprot ID: Q2G005
• Locus tag: SAGV51_RS04435
• Protein ID: WP_000052078.1
• Coordinates: 912559..912747 (-)
• Length: 63 a.a.

Antitoxin (Protein)

• Gene name: TsaA
• Uniprot ID: -
• Locus tag: SAGV51_RS04440
• Protein ID: WP_148563116.1
• Coordinates: 912781..913035 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAGV51_RS04405	908079..908765	+	687	WP_001548082.1	thermonuclease family protein	-
SAGV51_RS04410	909085..910257	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
SAGV51_RS04415	910454..910654	+	201	WP_001059082.1	cold-shock protein	-
SAGV51_RS04420	911150..911368	-	219	WP_000005886.1	hypothetical protein	-
SAGV51_RS04425	911430..911714	-	285	WP_001004395.1	hypothetical protein	-
SAGV51_RS04430	911802..912371	-	570	WP_001106654.1	hypothetical protein	-
SAGV51_RS04435	912559..912747	-	189	WP_000052078.1	hypothetical protein	Toxin
SAGV51_RS04440	912781..913035	-	255	WP_148563116.1	hypothetical protein	Antitoxin
SAGV51_RS04445	913376..913579	+	204	WP_000145163.1	sterile alpha motif-like domain-containing protein	-
SAGV51_RS04450	913576..913812	-	237	WP_000368687.1	hypothetical protein	-
SAGV51_RS04455	914037..914618	+	582	WP_001140686.1	phosphoglycerate mutase family protein	-
SAGV51_RS04460	914691..915308	-	618	WP_000255561.1	LysE/ArgO family amino acid transporter	-
SAGV51_RS04465	915463..915957	-	495	WP_000569884.1	GNAT family N-acetyltransferase	-
SAGV51_RS04470	916356..916778	-	423	WP_000974460.1	organic hydroperoxide resistance protein	-
SAGV51_RS04475	916926..917642	+	717	WP_000150017.1	type I 3-dehydroquinate dehydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	905911..937146	31235
	-	flank	IS/Tn	-	-	909085..910257	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 63 a.a.
• Molecular weight: 7172.84 Da
• Isoelectric Point: 9.9971

>T55485 WP_000052078.1 NZ_CP012015:c912747-912559 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTSKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Nucleotide

• Length: 189 bp

>T55485 NZ_CP012015:c912747-912559 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTAGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9697.90 Da
• Isoelectric Point: 4.0624

>AT55485 WP_148563116.1 NZ_CP012015:c913035-912781 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FIVL

Nucleotide

• Length: 255 bp

>AT55485 NZ_CP012015:c913035-912781 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATCGTATCCTTTACCATTG
CAATGATAACTAAAAACTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTATAGTTTTATAG

Structures

Toxin

• AlphaFold DB: A0A0D6HZ40