Detailed information of TA system TA055404

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 8227..8764
• Replicon: plasmid unnamed
• Accession: NZ_CP012003
• Organism: Xanthomonas citri pv. aurantifolii strain 1566

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AC028_RS22325
• Protein ID: WP_088412134.1
• Coordinates: 8483..8764 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7X9UWY6
• Locus tag: AC028_RS22320
• Protein ID: WP_017158384.1
• Coordinates: 8227..8496 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AC028_RS22295	4810..5511	-	702	WP_007962299.1	UPF0149 family protein	-
AC028_RS22300	5728..5907	-	180	WP_082332505.1	hypothetical protein	-
AC028_RS22310	6311..6997	+	687	WP_007968793.1	DNA-binding protein	-
AC028_RS22315	7156..8118	+	963	WP_007968792.1	recombinase family protein	-
AC028_RS22320	8227..8496	+	270	WP_017158384.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AC028_RS22325	8483..8764	+	282	WP_088412134.1	type II toxin-antitoxin system YafQ family toxin	Toxin
AC028_RS22330	9084..9485	-	402	WP_007968789.1	hypothetical protein	-
AC028_RS22335	9644..9997	-	354	WP_042676252.1	hypothetical protein	-
AC028_RS22340	10043..10750	-	708	WP_007968786.1	hypothetical protein	-
AC028_RS22345	10747..11202	-	456	WP_007968784.1	hypothetical protein	-
AC028_RS22350	11591..12037	+	447	WP_007968782.1	hypothetical protein	-
AC028_RS22360	12558..13202	+	645	WP_007968779.1	hypothetical protein	-
AC028_RS22365	13248..13574	-	327	WP_007968778.1	type II toxin-antitoxin system PemK/MazF family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..35521	35521

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-93)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-86)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10689.10 Da
• Isoelectric Point: 8.9188

>T55404 WP_088412134.1 NZ_CP012003:8483-8764 [Xanthomonas citri pv. aurantifolii]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGPHSELFG

Nucleotide

• Length: 282 bp

>T55404 NZ_CP012003:8483-8764 [Xanthomonas citri pv. aurantifolii]
ATGCGGACGATTGACCGTTCATCCGCTTTCAAGCGCGACTACAAGCGGGAAGCCAAGGGGCAGCATCGCGCCACGCTTGA
TGACGCGATCAAGCCGGTGTTGGTCGCACTGGCGACCGATCAGCCTCCCGATGCACGCTATCGCGATCACGATCTTTCCG
GCGATTGGGCGGGCTATCGGGAATGTCACATCAAGCCCGACTTGCTGCTGATCTACCGCAAGTCCGACCCCGACACCCTG
CGACTGGCACGGCTTGGCCCGCACAGCGAGCTTTTCGGCTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9719.10 Da
• Isoelectric Point: 5.6976

>AT55404 WP_017158384.1 NZ_CP012003:8227-8496 [Xanthomonas citri pv. aurantifolii]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Nucleotide

• Length: 270 bp

>AT55404 NZ_CP012003:8227-8496 [Xanthomonas citri pv. aurantifolii]
ATGAGCACTACCGCCGATACCTACGTCCGCGCCCGCATCGACACCGCCACCAAGGAACGTGCCGCTAGTGCGCTCGAAGC
AATGGGGCTGTCGATCTCTGATGCTATCCGCCTGCTGATGCTACGCATTGCCGACGAACACCGCCTGCCCTTCGATGTGA
AGGTACCAAACACCACCACGAAAAAGGCGATTGCCGAACTGGAATCAGGCAAGGGTAAGAAGTTCGCCAATGTGGACGAC
CTGATGGCGGATTTGCATGCGGACGATTGA

Structures

Antitoxin

• AlphaFold DB: A0A7X9UWY6