55402

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 948850..949211 Replicon chromosome
Accession NZ_CP012002
Organism Xanthomonas citri pv. aurantifolii strain 1566

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag AC028_RS04310 Protein ID WP_005914328.1
Coordinates 948850..948984 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag AC028_RS04315 Protein ID WP_003486606.1
Coordinates 949059..949211 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC028_RS04295 945879..946922 - 1044 WP_007966943.1 MBL fold metallo-hydrolase -
AC028_RS04300 946952..948241 - 1290 WP_007966942.1 tryptophan--tRNA ligase -
AC028_RS04305 948414..948623 - 210 WP_042675974.1 CsbD family protein -
AC028_RS04310 948850..948984 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
AC028_RS04315 949059..949211 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
AC028_RS04320 949318..950241 - 924 WP_007966941.1 arginase -
AC028_RS04325 950562..951014 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
AC028_RS04330 951078..951437 + 360 WP_003486613.1 hypothetical protein -
AC028_RS04335 951534..952451 + 918 WP_007966939.1 hypothetical protein -
AC028_RS04340 952448..952990 + 543 WP_003486615.1 GTPase -
AC028_RS04345 953470..954153 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T55402 WP_005914328.1 NZ_CP012002:c948984-948850 [Xanthomonas citri pv. aurantifolii]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T55402 NZ_CP012002:c948984-948850 [Xanthomonas citri pv. aurantifolii]
ATGAAGCGTGCAATTGTGCTGCTGGTGTTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT55402 WP_003486606.1 NZ_CP012002:c949211-949059 [Xanthomonas citri pv. aurantifolii]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55402 NZ_CP012002:c949211-949059 [Xanthomonas citri pv. aurantifolii]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References