Detailed information of TA system TA055392

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 2284741..2285563
• Replicon: chromosome
• Accession: NZ_CP011994
• Organism: Ectothiorhodospira sp. BSL-9

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: A0A167AX19
• Locus tag: ECTOBSL9_RS10715
• Protein ID: WP_063465040.1
• Coordinates: 2284741..2285178 (-)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: A0A167AX35
• Locus tag: ECTOBSL9_RS10720
• Protein ID: WP_063465041.1
• Coordinates: 2285168..2285563 (-)
• Length: 132 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ECTOBSL9_RS10695	2280997..2281926	-	930	WP_063465036.1	ornithine carbamoyltransferase	-
ECTOBSL9_RS10700	2281936..2283114	-	1179	WP_063465037.1	acetylornithine transaminase	-
ECTOBSL9_RS10705	2283341..2283925	-	585	WP_063465038.1	superoxide dismutase	-
ECTOBSL9_RS10710	2284098..2284652	-	555	WP_063465039.1	glutathione peroxidase	-
ECTOBSL9_RS10715	2284741..2285178	-	438	WP_063465040.1	DUF86 domain-containing protein	Toxin
ECTOBSL9_RS10720	2285168..2285563	-	396	WP_063465041.1	nucleotidyltransferase domain-containing protein	Antitoxin
ECTOBSL9_RS10725	2285712..2287487	+	1776	WP_063465042.1	N-acetylglutaminylglutamine amidotransferase	-
ECTOBSL9_RS10730	2287608..2287925	+	318	WP_063466148.1	Grx4 family monothiol glutaredoxin	-
ECTOBSL9_RS10735	2287933..2288895	-	963	WP_082829875.1	diguanylate cyclase	-
ECTOBSL9_RS10740	2288955..2289605	-	651	WP_063466149.1	ribonuclease T	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (18-131)

Antitoxin

• Polymerase beta, nucleotidyltransferase (6-88)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 16392.70 Da
• Isoelectric Point: 7.4347

>T55392 WP_063465040.1 NZ_CP011994:c2285178-2284741 [Ectothiorhodospira sp. BSL-9]
MVDDVLLNKAATIERCVARAREEYAANPEGFHQDYTRQDAAILNIQRACEAALDMGQHLIRRERLGAPQSARDVFTLLHR
GGWIEADLADVLKRMVGFRNIAVHDYQSLQIAITISIIKHHLDDFLAYSSRILKADARREAGNKP

Nucleotide

• Length: 438 bp

>T55392 NZ_CP011994:c2285178-2284741 [Ectothiorhodospira sp. BSL-9]
ATGGTGGATGATGTCCTGCTCAACAAGGCAGCCACCATCGAGCGCTGCGTGGCCCGGGCCCGAGAGGAGTATGCGGCCAA
TCCCGAGGGATTCCACCAGGACTACACGCGCCAGGATGCGGCGATCCTCAACATACAGAGGGCCTGCGAAGCGGCTCTGG
ACATGGGACAGCACCTGATCCGCCGCGAACGCCTGGGCGCGCCTCAGAGTGCCCGGGACGTCTTCACGCTGCTGCATCGC
GGCGGCTGGATCGAGGCGGATCTGGCTGATGTCCTGAAACGCATGGTGGGCTTTCGGAATATCGCGGTTCACGATTACCA
GAGCCTGCAGATAGCCATCACCATCAGCATCATCAAACACCATCTGGATGATTTTCTGGCCTATTCCAGTCGTATCCTGA
AGGCTGATGCTCGGCGGGAGGCCGGCAACAAGCCCTGA

Antitoxin

Protein

• Length: 132 a.a.
• Molecular weight: 14210.19 Da
• Isoelectric Point: 4.4493

>AT55392 WP_063465041.1 NZ_CP011994:c2285563-2285168 [Ectothiorhodospira sp. BSL-9]
MNQAEIIQRLQDRVPGLMGIYAFGSRIHGTAGPDSDLDLAVLVAGYADVLLLWEVSGELADVAGCPVDLVDLRAASTVMQ
YQIITRGERWWALDTRTALYEAAILSEKTELDTARAGLLEDIGKRGRVHGG

Nucleotide

• Length: 396 bp

>AT55392 NZ_CP011994:c2285563-2285168 [Ectothiorhodospira sp. BSL-9]
ATGAATCAGGCAGAGATCATTCAGCGACTGCAAGACCGGGTGCCGGGGCTCATGGGCATTTATGCCTTTGGCAGCCGCAT
TCACGGAACGGCCGGGCCCGACAGTGACCTGGACCTGGCGGTGCTGGTGGCGGGATATGCCGATGTCCTGCTGCTCTGGG
AGGTCTCCGGCGAACTGGCGGATGTGGCGGGCTGCCCGGTGGACCTGGTGGATCTACGGGCTGCCTCCACGGTGATGCAA
TATCAGATCATCACCCGCGGGGAGCGCTGGTGGGCCCTGGATACCCGCACCGCGCTCTACGAAGCCGCCATACTCAGCGA
GAAGACCGAACTCGACACGGCCCGCGCGGGCCTGCTGGAGGATATCGGCAAACGGGGGCGGGTCCATGGTGGATGA

Structures

Toxin

• AlphaFold DB: A0A167AX19

Antitoxin

• AlphaFold DB: A0A167AX35