Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 979774..980404 Replicon chromosome
Accession NZ_CP011994
Organism Ectothiorhodospira sp. BSL-9

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ECTOBSL9_RS04730 Protein ID WP_205632018.1
Coordinates 980117..980404 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A167BMF6
Locus tag ECTOBSL9_RS04725 Protein ID WP_063466008.1
Coordinates 979774..980112 (-) Length 113 a.a.

Genomic Context

ECTOBSL9_RS04715ECTOBSL9_RS04720ECTOBSL9_RS16395ECTOBSL9_RS04725ECTOBSL9_RS04730ECTOBSL9_RS04735ECTOBSL9_RS16870ECTOBSL9_RS04745
Location: 975958..976809 (852 bp)
Type: Others
Protein ID: WP_063464103.1
Location: 976927..979026 (2100 bp)
Type: Others
Protein ID: WP_063466007.1
Location: 979211..979665 (455 bp)
Type: Others
Protein ID: Protein_943
Location: 979774..980112 (339 bp)
Type: Antitoxin
Protein ID: WP_063466008.1
Location: 980117..980404 (288 bp)
Type: Toxin
Protein ID: WP_205632018.1
Location: 980816..981823 (1008 bp)
Type: Others
Protein ID: WP_168161531.1
Location: 981891..982880 (990 bp)
Type: Others
Protein ID: WP_156500039.1
Location: 982804..984219 (1416 bp)
Type: Others
Protein ID: WP_063464107.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ECTOBSL9_RS04715975958..976809+852WP_063464103.1universal stress protein-
ECTOBSL9_RS04720976927..979026+2100WP_063466007.1AAA family ATPase-
ECTOBSL9_RS16395979211..979665-455Protein_943VOC family protein-
ECTOBSL9_RS04725979774..980112-339WP_063466008.1putative addiction module antidote proteinAntitoxin
ECTOBSL9_RS04730980117..980404-288WP_205632018.1type II toxin-antitoxin system RelE/ParE family toxinToxin
ECTOBSL9_RS04735980816..981823-1008WP_168161531.1hypothetical protein-
ECTOBSL9_RS16870981891..982880-990WP_156500039.1hypothetical protein-
ECTOBSL9_RS04745982804..984219-1416WP_063464107.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--966348..99066024312


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-92)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10653.19 Da        Isoelectric Point: 10.5350

>T55389 WP_205632018.1 NZ_CP011994:c980404-980117 [Ectothiorhodospira sp. BSL-9]
IQTTSTFDAWFESLRDRQGKARIAARLRRLEMGHMGDAKAVGKGVQEMRIDCGPGYRIYFTRRGIEIVILLAGGDKDSQQ
RDIRAATTLARQIGD

Download         Length: 288 bp

>T55389 NZ_CP011994:c980404-980117 [Ectothiorhodospira sp. BSL-9]
ATCCAGACAACCAGTACGTTCGATGCGTGGTTCGAGTCACTGCGGGATCGGCAAGGCAAGGCCCGGATTGCAGCCCGATT
GCGGCGCCTGGAGATGGGGCACATGGGCGACGCGAAGGCGGTTGGCAAGGGCGTGCAGGAGATGCGGATCGACTGCGGCC
CCGGATACCGGATTTACTTTACCCGGCGGGGCATCGAGATCGTGATCCTGTTGGCTGGTGGCGACAAGGACTCCCAGCAA
CGGGATATACGCGCGGCCACGACGCTGGCCCGGCAGATTGGAGACTGA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12250.81 Da        Isoelectric Point: 5.1498

>AT55389 WP_063466008.1 NZ_CP011994:c980112-979774 [Ectothiorhodospira sp. BSL-9]
MTDVTLKRWDAVDHLHTDEDMALYLDACFAEDPGDGSLIRAALGDIARARGMTQLARDTGMAREGLYKALSSEGNPEFNT
IIKVVRALGLRLHAQSANENREPGVSVQSRPL

Download         Length: 339 bp

>AT55389 NZ_CP011994:c980112-979774 [Ectothiorhodospira sp. BSL-9]
ATGACCGACGTGACGCTGAAGCGCTGGGACGCAGTGGACCACCTCCACACTGACGAGGACATGGCCCTCTACCTCGACGC
CTGCTTCGCTGAAGATCCCGGGGACGGAAGCCTGATCCGGGCCGCGCTCGGAGACATTGCCCGAGCCCGCGGTATGACCC
AACTAGCCCGGGACACCGGCATGGCTCGCGAGGGACTGTACAAGGCGCTGTCCAGCGAGGGAAACCCTGAGTTCAACACG
ATCATAAAGGTTGTGCGCGCCCTCGGGCTTCGGCTGCACGCCCAAAGTGCGAACGAGAACCGGGAACCCGGCGTCTCGGT
GCAGTCGCGGCCACTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A167BMF6

References