Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 708439..708865 Replicon chromosome
Accession NZ_CP011994
Organism Ectothiorhodospira sp. BSL-9

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag ECTOBSL9_RS16380 Protein ID WP_082829715.1
Coordinates 708686..708865 (-) Length 60 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A167A6T7
Locus tag ECTOBSL9_RS03535 Protein ID WP_063463902.1
Coordinates 708439..708696 (-) Length 86 a.a.

Genomic Context

ECTOBSL9_RS17230ECTOBSL9_RS03520ECTOBSL9_RS03525ECTOBSL9_RS16365ECTOBSL9_RS16370ECTOBSL9_RS16375ECTOBSL9_RS03530ECTOBSL9_RS03535ECTOBSL9_RS16380ECTOBSL9_RS03540ECTOBSL9_RS03550ECTOBSL9_RS03555ECTOBSL9_RS03560
Location: 704237..704755 (519 bp)
Type: Others
Protein ID: WP_205631990.1
Location: 704755..705801 (1047 bp)
Type: Others
Protein ID: WP_063463901.1
Location: 705838..706031 (194 bp)
Type: Others
Protein ID: Protein_700
Location: 706028..706282 (255 bp)
Type: Others
Protein ID: Protein_701
Location: 706349..706648 (300 bp)
Type: Others
Protein ID: WP_082829712.1
Location: 706645..706884 (240 bp)
Type: Others
Protein ID: WP_082829713.1
Location: 707661..708413 (753 bp)
Type: Others
Protein ID: WP_082829714.1
Location: 708439..708696 (258 bp)
Type: Antitoxin
Protein ID: WP_063463902.1
Location: 708686..708865 (180 bp)
Type: Toxin
Protein ID: WP_082829715.1
Location: 708858..710416 (1559 bp)
Type: Others
Protein ID: Protein_707
Location: 710536..711795 (1260 bp)
Type: Others
Protein ID: WP_063463905.1
Location: 712363..712515 (153 bp)
Type: Others
Protein ID: WP_082829716.1
Location: 712865..713551 (687 bp)
Type: Others
Protein ID: WP_156500028.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ECTOBSL9_RS17230704237..704755+519WP_205631990.1helix-turn-helix domain-containing protein-
ECTOBSL9_RS03520704755..705801+1047WP_063463901.1IS3 family transposase-
ECTOBSL9_RS03525705838..706031+194Protein_700type II toxin-antitoxin system prevent-host-death family antitoxin-
ECTOBSL9_RS16365706028..706282+255Protein_701Txe/YoeB family addiction module toxin-
ECTOBSL9_RS16370706349..706648-300WP_082829712.1type II toxin-antitoxin system RelE/ParE family toxin-
ECTOBSL9_RS16375706645..706884-240WP_082829713.1addiction module protein-
ECTOBSL9_RS03530707661..708413-753WP_082829714.1endonuclease/exonuclease/phosphatase family protein-
ECTOBSL9_RS03535708439..708696-258WP_063463902.1hypothetical proteinAntitoxin
ECTOBSL9_RS16380708686..708865-180WP_082829715.1BrnT family toxinToxin
ECTOBSL9_RS03540708858..710416-1559Protein_707IS3 family transposase-
ECTOBSL9_RS03550710536..711795-1260WP_063463905.1group II intron reverse transcriptase/maturase-
ECTOBSL9_RS03555712363..712515-153WP_082829716.1BrnT family toxin-
ECTOBSL9_RS03560712865..713551-687WP_156500028.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--704755..72612021365
-flankIS/Tn--702951..7042041253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(15-53)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6656.72 Da        Isoelectric Point: 11.4422

>T55388 WP_082829715.1 NZ_CP011994:c708865-708686 [Ectothiorhodospira sp. BSL-9]
MHNDALSGDNIIDSRRPRTLVIGTIGTKVWSAIITYRKGTIRIISVRRARKSEVALYES

Download         Length: 180 bp

>T55388 NZ_CP011994:c708865-708686 [Ectothiorhodospira sp. BSL-9]
CTGCATAACGATGCACTCTCAGGCGACAACATCATTGACAGCCGCCGGCCCCGGACGTTGGTTATTGGCACCATTGGAAC
GAAGGTGTGGTCGGCAATAATTACCTACCGGAAGGGCACCATCCGCATCATCTCGGTCAGAAGGGCGCGGAAATCAGAGG
TGGCACTGTATGAAAGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9994.36 Da        Isoelectric Point: 5.9025

>AT55388 WP_063463902.1 NZ_CP011994:c708696-708439 [Ectothiorhodospira sp. BSL-9]
MKAEELDKRFDDNEEDLLEHLDLKTAKRPNQVQKRVNVDFPIWMIESLDREASRLGVTRQSIIKVWLAERLEEAAANKAC
QRTSR

Download         Length: 258 bp

>AT55388 NZ_CP011994:c708696-708439 [Ectothiorhodospira sp. BSL-9]
ATGAAAGCTGAAGAGTTAGATAAAAGGTTCGACGATAACGAAGAAGATCTACTAGAACACCTTGATCTAAAAACCGCAAA
GCGTCCGAATCAGGTGCAGAAGCGGGTTAACGTAGACTTTCCCATTTGGATGATCGAGTCGCTCGACCGTGAAGCGAGTC
GCTTAGGTGTTACTAGGCAGTCAATCATAAAGGTATGGCTCGCCGAGCGTTTAGAAGAAGCGGCTGCTAACAAAGCATGT
CAGCGGACAAGCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A167A6T7

References