Detailed information of TA system TA055388

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 708439..708865
• Replicon: chromosome
• Accession: NZ_CP011994
• Organism: Ectothiorhodospira sp. BSL-9

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: ECTOBSL9_RS16380
• Protein ID: WP_082829715.1
• Coordinates: 708686..708865 (-)
• Length: 60 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A167A6T7
• Locus tag: ECTOBSL9_RS03535
• Protein ID: WP_063463902.1
• Coordinates: 708439..708696 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ECTOBSL9_RS17230	704237..704755	+	519	WP_205631990.1	helix-turn-helix domain-containing protein	-
ECTOBSL9_RS03520	704755..705801	+	1047	WP_063463901.1	IS3 family transposase	-
ECTOBSL9_RS03525	705838..706031	+	194	Protein_700	type II toxin-antitoxin system prevent-host-death family antitoxin	-
ECTOBSL9_RS16365	706028..706282	+	255	Protein_701	Txe/YoeB family addiction module toxin	-
ECTOBSL9_RS16370	706349..706648	-	300	WP_082829712.1	type II toxin-antitoxin system RelE/ParE family toxin	-
ECTOBSL9_RS16375	706645..706884	-	240	WP_082829713.1	addiction module protein	-
ECTOBSL9_RS03530	707661..708413	-	753	WP_082829714.1	endonuclease/exonuclease/phosphatase family protein	-
ECTOBSL9_RS03535	708439..708696	-	258	WP_063463902.1	hypothetical protein	Antitoxin
ECTOBSL9_RS16380	708686..708865	-	180	WP_082829715.1	BrnT family toxin	Toxin
ECTOBSL9_RS03540	708858..710416	-	1559	Protein_707	IS3 family transposase	-
ECTOBSL9_RS03550	710536..711795	-	1260	WP_063463905.1	group II intron reverse transcriptase/maturase	-
ECTOBSL9_RS03555	712363..712515	-	153	WP_082829716.1	BrnT family toxin	-
ECTOBSL9_RS03560	712865..713551	-	687	WP_156500028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	704755..726120	21365
	-	flank	IS/Tn	-	-	702951..704204	1253

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (15-53)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6656.72 Da
• Isoelectric Point: 11.4422

>T55388 WP_082829715.1 NZ_CP011994:c708865-708686 [Ectothiorhodospira sp. BSL-9]
MHNDALSGDNIIDSRRPRTLVIGTIGTKVWSAIITYRKGTIRIISVRRARKSEVALYES

Nucleotide

• Length: 180 bp

>T55388 NZ_CP011994:c708865-708686 [Ectothiorhodospira sp. BSL-9]
CTGCATAACGATGCACTCTCAGGCGACAACATCATTGACAGCCGCCGGCCCCGGACGTTGGTTATTGGCACCATTGGAAC
GAAGGTGTGGTCGGCAATAATTACCTACCGGAAGGGCACCATCCGCATCATCTCGGTCAGAAGGGCGCGGAAATCAGAGG
TGGCACTGTATGAAAGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9994.36 Da
• Isoelectric Point: 5.9025

>AT55388 WP_063463902.1 NZ_CP011994:c708696-708439 [Ectothiorhodospira sp. BSL-9]
MKAEELDKRFDDNEEDLLEHLDLKTAKRPNQVQKRVNVDFPIWMIESLDREASRLGVTRQSIIKVWLAERLEEAAANKAC
QRTSR

Nucleotide

• Length: 258 bp

>AT55388 NZ_CP011994:c708696-708439 [Ectothiorhodospira sp. BSL-9]
ATGAAAGCTGAAGAGTTAGATAAAAGGTTCGACGATAACGAAGAAGATCTACTAGAACACCTTGATCTAAAAACCGCAAA
GCGTCCGAATCAGGTGCAGAAGCGGGTTAACGTAGACTTTCCCATTTGGATGATCGAGTCGCTCGACCGTGAAGCGAGTC
GCTTAGGTGTTACTAGGCAGTCAATCATAAAGGTATGGCTCGCCGAGCGTTTAGAAGAAGCGGCTGCTAACAAAGCATGT
CAGCGGACAAGCCGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A167A6T7